Table 1

Baseline behaviors in CentA1 null (n = 23) and CentA1 NTG littermates (n = 28)

Behavioral test	Measurement	Testing for	CentA1 KO	NTG	Statistical significance	Statistical test
OF	Distance moved (cm)	Activity levels	2964.3 ± 140.8	2794.57 ± 137.67	p = 0.39 (not significant)	t test
OF	Exit latency (s)	Anxiety	3.72 ± 0.70	2.45 ± 0.53	p = 0.15 (not significant)	t test
EPM	Time spent in open arm (%)	Anxiety-like behavior	16.56 ± 4.10	22.90 ± 3.82	p = 0.26 (not significant)	t test
RR	Time spent on rod over three trials (s)	Motor coordination and balance	123.67 ± 10.26	139.58 ± 9.16	p = 0.25 (not significant)	t test
MWM	Swim speed (cm/s)	Motor ability	18.81 ± 0.62 cm/s (probe trial)	20.09 ± 0.47 cm/s (probe trial)	p = 0.11 (not significant)	t test
MWM-VPT	Latency to visible platform (s)	Visual acuity	18.28 ± 1.35	18.15 ± 1.28	p = 0.94 (not significant)	t test
SA	Alternation success between two mazes (%)	Working memory	66.67 ± 10.54	80.00 ± 8.16	p = 0.33 (not significant)	t test

Table shows the behavioral tests that were performed to identify potential abnormalities in baseline behaviors of CentA1 KO mice. On all measures, there was no statistically significant difference between the CentA1 KO mice and their wild-type littermates.