The effects of inhibitors on AII eEPSC amplitude and mEPSC frequency
Data | Data structure | Type of test | Power | Mean ± SEM | Number of cells | |
---|---|---|---|---|---|---|
Effect on AII eEPSC amplitude | ||||||
Control | Non-normal distribution | 1.00 ± 0.00 | ||||
50 μm W-7 | Normal distribution | 0.28 ± 0.05 | 9 | |||
100 μm ML-9 | Non-normal distribution | 0.12 ± 0.04 | 10 | |||
4 μm KN-62 | Normal distribution | 0.85 ± 0.07 | 10 | |||
40 μm MMPX | Non-normal distribution | 0.82 ± 0.16 | 8 | |||
1 μm ascomycin | Normal distribution | 0.73 ± 0.07 | 8 | |||
a | Control vs W-7 | Wilcoxon signed-rank test | p = 0.0039 | 9 | ||
b | Control vs ML-9 | Wilcoxon signed-rank test | p = 0.0020 | 10 | ||
c | Control vs KN-62 | Wilcoxon signed-rank test | p = 0.0586 | 10 | ||
d | Control vs MMPX | Wilcoxon signed-rank test | p = 0.4609 | 8 | ||
e | Control vs ascomycin | Wilcoxon signed-rank test | p = 0.0078 | 8 | ||
Effect on AII mEPSC frequency | ||||||
Control | Non-normal distribution | 1.00 ± 0.00 | ||||
50 μm W-7 | Non-normal distribution | 5.95 ± 0.86 | 15 | |||
100 μm ML-9 | Normal distribution | 7.19 ± 1.32 | 10 | |||
4 μm KN-62 | Normal distribution | 0.88 ± 0.07 | 11 | |||
40 μm MMPX | Normal distribution | 1.35 ± 0.23 | 8 | |||
1 μm ascomycin | Normal distribution | 0.94 ± 0.10 | 15 | |||
f | Control vs W-7 | Wilcoxon signed-rank test | p < 0.0001 | 15 | ||
g | Control vs ML-9 | Wilcoxon signed-rank test | p = 0.0020 | 10 | ||
h | Control vs KN-62 | Wilcoxon signed-rank test | p = 0.2139 | 11 | ||
i | Control vs MMPX | Wilcoxon signed-rank test | p = 0.3828 | 8 | ||
j | Control vs ascomycin | Wilcoxon signed-rank test | p = 0.3591 | 15 |