Distribution of ER in spines
| Brain region | Spines observed (n) | ER-containing spines (%) | Head volume (mean ± SD) | Neck length (mean ± SD) | Neck diameter (mean ± SD) | |||
|---|---|---|---|---|---|---|---|---|
| ER+ | ER– | ER+ | ER– | ER+ | ER– | |||
| CA1 PSR | 552 | 13.6 | 0.11 ± 0.073 | 0.04 ± 0.030*** | 0.46 ± 0.229 | 0.46 ± 0.249 | 0.25 ± 0.101 | 0.19 ± 0.082*** |
| CA1 SLM | 70 | 15.7 | 0.18 ± 0.077 | 0.11 ± 0.084* | 0.55 ± 0.233 | 0.48 ± 0.300 | 0.34 ± 0.090 | 0.23 ± 0.127** |
| Cortex | 221 | 40.3 | 0.15 ± 0.131 | 0.04 ± 0.023*** | 1.03 ± 0.566 | 1.13 ± 0.557 | 0.30 ± 0.143 | 0.19 ± 0.075*** |
| Striatum | 403 | 55.1 | 0.10 ± 0.137 | 0.02 ± 0.017*** | 1.15 ± 0.584 | 1.09 ± 0.518 | 0.29 ± 0.105 | 0.21 ± 0.085*** |
| CB | 824 | 100 | — | — | — | — | — | — |
Units: head volume, μm3; neck length, μm; neck diameter, μm.
Asterisks denote statistical significance in the dimensions of head volume and neck diameter between ER-containing (ER+) and ER-lacking spines (ER–) in each brain region.