Table 1

Means, SE, and sample sizes for 2D TEM morphological analyses

AgeTotal boutonsTotal synapsesPSD length (μm)Bouton area (μm2)% SBBsSpinule area (μm2)Spinule:bouton area (%)
p2170740.290.344%0.0412%
p2871780.270.427%0.026%
Group sum
Group mean ± SEM (n = animals)
1411520.28 ± 0.010.38 ± 0.036 ± 1.4%0.03 ± 0.019 ± 3.1%
Cumulative mean ± SEM (n = sampled structures)0.28 ± 0.010.38 ± 0.036 ± 1.4%0.03 ± 0.016 ± 1.5%
p461021020.280.196%0.026%
p4794940.290.216%0.0312%
Group sum
Group mean ± SEM (n = animals)
1961960.29 ± 0.010.20 ± 0.016 ± 0.3%0.03 ± 0.0019 ± 3.2%
Cumulative mean ± SEM (n = sampled structures)0.29 ± 0.010.20 ± 0.016 ± 0.3%0.02 ± 0.0048 ± 3.2%
p60_125290.280.2110%0.0414%
p60_21111130.290.2813%0.014%
p66_11181240.310.2811%0.0414%
Group sum
Group mean ± SEM (n = animals)
2542660.30 ± 0.010.26 ± 0.0211 ± 0.8%0.03 ± 0.0111 ± 3.4%
Cumulative mean ± SEM (n = sampled structures)0.30 ± 0.010.27 ± 0.0111 ± 0.8%0.03 ± 0.0110 ± 1.7
>p90_161610.320.2916%0.0616%
>p90_21491500.360.3315%0.025%
>p90_31091120.340.3522%0.044%
Group sum
Group mean ± SEM (n = animals)
3193230.35 ± 0.010.32 ± 0.0118 ± 2.1%0.04 ± 0.018 ± 4%
Cumulative mean ± SEM (n = sampled structures)0.35 ± 0.010.33 ± 0.0118 ± 2.1%0.04 ± 0.018 ± 1%
  • Means and SEM for individual animals and developmental age groups are listed for each 2D TEM analysis measurement (column titles). Population sizes are listed for individual animals and age groups under total boutons and total synapses columns. % SBBs = percentage of sampled excitatory presynaptic boutons that contained spinules. Spinule: bouton area % = percentage of bouton area occupied by spinule area.