Model parameters (see Extended Data Table 1-1 for full list)
| Parameter | Description | DA neuron | GABA neuron |
|---|---|---|---|
| Amplitude of Ach input | 5 μM | 10 μM | |
| Amplitude of Nic input | 0.5 μM | 0.5 μM | |
| w | Potency of Nic to evoke response | 3 | 3 |
| GABAR conductance | 2.5 mS/cm2 | ||
| NMDAR conductance | 4 mS/cm2 | 0 mS/cm2 | |
| Leak conductance | 0.03 mS/cm2 | 0.05 + 0.05(rnd-0.5) mS/cm2 |