Table 1

Cellular excitability measures for motoneurons and interneurons following different treatments in vitro and in vivo

ConditionMotoneuronRheobase(pA)MotoneuronVm – Vt(mV)MotoneuronRMP (mV)MotoneuronRm (MΩ)InterneuronRheobase(pA)InterneuronVm – Vt
(mV)
InterneuronRMP
(mV)
Interneuron
Rm
(MΩ)
Controls in vivo 81.8 ± 4.330.3 ± 1.6–68.1 ± 1.3599.6 ± 13.884.1 ± 8.334.7 ± 2.7–70.2 ± 2.2578.5 ± 49.0
GABAAR blockers6 h in vivo 41.7 ± 14.0 19.7 ± 3.1 –62.9 ± 2.5584.3 ± 23.9 29.1 ± 5.3 21.5 ± 2.1 –61.1 ± 1.7 701.7 ± 57.3
GABAAR blockers12 h in vivo 47.3±5.3 26.8 ± 2.9–72.7 ± 2.4657.2 ± 67.3 20.6 ± 3.7 21.1 ± 2.3–66.0 ± 2.2624.8 ± 88.1
Controls in vitro 74.3 ± 6.734.5 ± 2.1–68.0 ± 1.4537.2 ± 30.681.6 ± 5.733.7 ± 1.8–71.3 ± 1.5560.8 ± 40.9
GABAAR blockers0–2 h in vitro 57.8 ± 7.120.3 ± 1.3 –59.6 ± 1.8 432.3 ± 37.3 37.0 ± 6.9 16.3 ± 1.4 –55.6 ± 1.1 494.6 ± 58.7
GABAAR blockers2–4 h in vitro 21.8 ± 7.2 28.1 ± 1.8 –58.6 ± 1.8 474.4 ± 22.0 35.7 ± 7.4 21.6 ± 1.4 –55.4 ± 1.3 550.56 ± 70.0
GABAAR blockers4–6 h in vitro 32.1 ± 6.3 20.0 ± 1.4 –60.3 ± 1.1 442.0 ± 41.0 16.5 ± 2.5 15.8 ± 1.5 –60.3 ± 1.5 582.5 ± 109.13
GluR blockers0–2 h in vitro 46.6 ± 10.3 18.6 ± 7.2 –57.4 ± 1.5 492.7 ± 76.1 34.3 ± 8.7 15.8 ± 1.1 –55.4 ± 1.1 555.9 ± 56.4
GluR blockers2–4 h in vitro 27.6 ± 7.4 19.1 ± 1.8 –59.0 ± 1.8 704.4 ± 54.3 13.7 ± 2.7 14.6 ± 1.5 –53.7 ± 1.1 687.1 ± 85.9
GluR blockers4–6 h in vitro 17.7 ± 4.2 16.1 ± 1.9 –58.0 ± 1.5 722.5 ± 54.1 12.2 ± 4.2 14.2 ± 1.1 –53.7 ± 0.9 776.7 ± 72.9
  • Numbers in bold are show significant difference with controls. Measures are averages ± SEs.