Summary of statistical analyses
| Figures | N | M and F | Age | Type of test | Factor | Statistical value | p |
|---|---|---|---|---|---|---|---|
| 2A | rTgFKBP5 (N = 10), WT (N = 10) | M and F | 4–6 months old | Student’s t test (unpaired, two-tailed) | Genotype | F = 25, DFn = 9 | p < 0.0001 |
| 3A | rTgFKBP5 (1M N = 16; 3M N = 26, 4M N = 21; 6M N = 7); WT (1M N = 19; 3M N = 33, 4M N = 26; 6M N = 6) tTA (1M N = 9; 3M N = 15, 4M N = 22; 6M N = 9) | M and F | Varies | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × age | F = 0.63; DFn = 6 | p = 0.705 |
| Genotype | F = 5.44; DFn = 2 | p = 0.005 | |||||
| Age | F = 48.97; DFn = 3 | p < 0.0001 | |||||
| 3B | rTgFKBP5 (N = 16), WT (N = 22), tTA (N = 20) | M and F | 3 months old | One-way ANOVA with Tukey post hoc test | Genotype | F = 0.8867 | p = 0.4178 |
| 3C | rTgFKBP5 (N = 16), WT (N = 22), tTA (N = 19) | M and F | 3 months old | One-way ANOVA with Tukey post hoc test | Genotype | F = 3.749 | p = 0.0299 |
| 3D | rTgFKBP5 (N = 16), WT (N = 22), tTA (N = 19) | M and F | 3 months old | One-way ANOVA with Tukey post hoc test | Genotype | F = 10.04 | p = 0.0002 |
| 3E | rTgFKBP5 (N = 16), WT (N = 22), tTA (N = 20) | M and F | 3 months old | One-way ANOVA with Tukey post hoc test | Genotype | F = 5.099 | p = 0.0093 |
| 3F | rTgFKBP5 (N = 16), WT (N = 22), tTA (N = 20) | M and F | 3 months old | One-way ANOVA with Tukey post hoc test | Genotype | F = 0.3405 | p = 0.7129 |
| 3G | rTgFKBP5 (N = 16), WT (N = 22), tTA (N = 20) | M and F | 3 months old | One-way ANOVA with Tukey post hoc test | Genotype | F = 4.094 | p = 0.0219 |
| 4A | rTgFKBP5 (N = 10), WT (N = 10), tTA (N = 10) | M and F | 4–6 months old | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × training day | F = 0.26; DFn = 6 | p = 0.9525 |
| Genotype | F = 7.39; DFn = 2 | p = 0.0010 | |||||
| Training day | F = 21.56; DFn = 3 | p < 0.0001 | |||||
| 4B | rTgFKBP5 (N = 10), WT (N = 10), tTA (N = 10) | M and F | 4–6 months old | One-way ANOVA with Tukey post hoc test | Quadrant time | rTgFKBP5: F = 9.948; WT: F = 31.30; tTA: F = 15.97 | rTgFKBP5: p < 0.0001; WT: p < 0.0001; tTA: p < 0.0001; |
| 4C | rTgFKBP5 (N = 10), WT (N = 10), tTA (N = 10) | M and F | 4–6 months old | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × training day | F = 0.82; DFn = 4 | p = 0.5146 |
| Genotype | F = 9.49; DFn = 2 | p = 0.0002 | |||||
| Training day | F = 12.66; DFn = 2 | p < 0.0001 | |||||
| 4D | rTgFKBP5 (N = 10), WT (N = 10), tTA (N = 10) | M and F | 4–6 months old | One-way ANOVA with Tukey post hoc test | Quadrant time | rTgFKBP5: F = 2.038; WT: F = 15.22; tTA: F = 31.26 | rTgFKBP5: p = 0.1259; WT: p < 0.0001; tTA: p < 0.0001 |
| 5A | rTgFKBP5 (N = 5; n = 18), WT (N = 6; n = 29), tTA (N = 5; n = 22) | M and F | 2–3.5 months old | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × time | F = 4.820; DFn = 158 | p < 0.0001 |
| Genotype | F = 1036 DFn = 2 | p < 0.0001 | |||||
| Time | F = 103.1; DFn = 79 | p < 0.0001 | |||||
| One-way ANOVA with Tukey post hoc test | Genotype | F = 872.5 | p < 0.0001 | ||||
| 5B | rTgFKBP5 (N = 7; n = 16), WT (N = 6; n = 23), and tTA (N = 8; n = 26) | M and F | 2–3.5 months old | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × time | F = 2.484; DFn= 164 | p < 0.0001 |
| Genotype | F = 344.9; DFn = 2 | p < 0.0001 | |||||
| Time | F = 117.6; DFn = 82 | p < 0.0001 | |||||
| One-way ANOVA with Tukey post hoc test of last 5 min of LTP | Genotype | F = 154.1 | p < 0.0001 | ||||
| 6A | rTgFKBP5 (N = 15; n = 65), WT (N = 15; n = 62), and tTA (N = 19; n = 77) | M and F | 2–3.5 months old | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × time | F = 2.562; DFn = 58 | p < 0.0001 |
| Genotype | F = 158.60; DFn = 2 | p < 0.0001 | |||||
| Time | F = 515.25; DFn = 29 | p < 0.0001 | |||||
| 6B | rTgFKBP5 (N = 15; n = 65), WT (N = 15; n = 62), and tTA (N = 19; n = 77) | M and F | 2–3.5 months old | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × time | F = 1.763; DFn = 58 | p = 0.0004 |
| Genotype | F = 117.2; DFn = 2 | p < 0.0001 | |||||
| Time | F = 239.1; DFn = 29 | p < 0.0001 | |||||
| 6D | rTgFKBP5 (N = 31; n = 175), WT (N = 33; n = 198), and tTA (N = 30; n = 181) | M and F | 2–3.5 months old | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × time | F = 0.7413; DFn = 28 | p = 0.8337 |
| Genotype | F = 44.78; DFn = 2 | p < 0.0001 | |||||
| Time | F = 50.97; DFn = 14 | p < 0.0001 | |||||
| 7 | rTgFKBP5 (N = 9; n = 21), WT (N = 9; n = 23), and tTA (N = 10; n = 31) | M and F | 2–3.5 months old | Two-way repeated-measures ANOVA with Bonferroni post hoc test | Genotype × time | F = 2.557 DFn = 158 | p < 0.0001 |
| Genotype | F = 561.9; DFn = 2 | p < 0.0001 | |||||
| Time | F = 33.52; DFn = 79 | p < 0.0001 | |||||
| One-way ANOVA with Tukey post hoc test of last 5 min of LTD | Genotype | F = 2065 | p < 0.0001 | ||||
| 8B | rTgFKBP5 (N = 4; n = 8), WT (N = 2; n = 4) and tTA (N = 2; n = 4) | M and F | 2–3 months old | Mann–Whitney test exact significance (two-tailed) | Between genotypes at 2 min | p = 0.3429 | |
| Between genotypes at 5 min | p = 0.0286 | ||||||
| Between genotypes at 10 min | p = 0.0286 | ||||||
| Between genotypes at 30 min | p = 0.1143 | ||||||