Table 4.

Developmental appearance of the 3-TF proxy for the LVST neuron group signature

StageMediocaudal vicinal groupLVST neuron groupMidbrain groupN preparationsSections assessed per preparation
(Lbx1+, Hoxb1-)(Lbx1+, Hoxb1+)(Lbx1-, Hoxb1-)
E9.50003Every 4th
E11.50, 0152, 59N/A2Every 4th
E13.531 ± 4203 ± 41145 ± 133Every 6th
E15.531 ± 13186 ± 66N/A3Every 6th
  • Mean (±SD) of Maf/Esrrg/Phox2b triple-positive hindbrain neurons at different locations (with indicated coexpression of either Lbx1 and/or Hoxb1) at different developmental stages in the mouse embryo. N/A, Not assessed.