Differences in area means between WT and KO | |||||||
---|---|---|---|---|---|---|---|
Age | WT (control); n = animals; N = litters | KO (test); n = animals; N = litters | Difference | 95% CI of difference | p value Mann– Whitney |
*<0.05
**<0.01 ***<0.005 ****<0.0001 | |
Total Midvermal Area | P3 | n = 6 N = 2 | n = 8 N = 1 | 0.22046525 | 0.1005809 to 0.33800371 | 0.02386844 | * |
Total Midvermal Area | P5 | n = 23 N = 10 | n = 19 N = 9 | –0.5345564 | –1.1207783 to –0.0094494 | 0.08802591 | ns |
Total Midvermal Area | P12 | n = 8 N = 2 | n = 8 N = 2 | –0.8547641 | –1.3264183 to –0.3690421 | 0.01008169 | * |
Total Midvermal Area | 2 months | n = 23 N = 6 | n = 11 N = 5 | –1.544694 | –2.3539983 to –0.929924 | 0.00040931 | *** |
lobes I–III | P3 | n = 6 N = 2 | n = 8 N = 1 | 0.00060315 | –0.0444497 to 0.04175221 | 0.94853252 | ns |
lobes I–III | P5 | n = 23 N = 10 | n = 19 N = 9 | –0.3107878 | –0.4960554 to –0.1219811 | 0.00145207 | *** |
lobes I–III | P12 | n = 8 N = 2 | n = 8 N = 2 | –0.5471343 | –0.7196807 to 0.4179097 | 0.00093911 | *** |
lobes I–III | 2 months | n = 23 N = 6 | n = 11 N = 5 | –0.9491027 | –1.1671892 to –0.7593015 | 1.1904E-06 | **** |
lobes IX–X | 2 months | n = 21 N = 6 | n = 11 N = 5 | –0.384772 | –0.5777334 to –0.2250031 | 0.00064456 | *** |
Differences in ratio of subregions over total midvermal areas between WT and KO | |||||||
I–III/total | P3 | n = 6 N = 2 | n = 8 N = 1 | –0.0465324 | –0.0774791 to –0.0181734 | 0.02386844 | * |
I–III/total | P5 | n = 23 N = 10 | n = 19 N = 9 | –0.0725127 | –0.0951794 to –0.0456856 | 2.4409E-05 | **** |
I–III/total | P12 | n = 8 N = 2 | n = 8 N = 2 | –0.0728148 | –0.0866715 to –0.0584468 | 0.00093911 | *** |
I–III/total | 2 months | n = 21 N = 6 | n = 11 N = 5 | –0.0391941 | –0.0483767 to –0.0289259 | 1.275E-05 | **** |
IX–X/total | 2 months | n = 21 N = 6 | n = 11 N = 5 | –0.0046574 | –0.012602 to 0.0042559 | 0.40473443 | ns |