Table 4

Normalized linear and 2° regression coefficients for propagation and oscillation in heterogeneously varied synaptic networks

Normalized regression coefficients in heterogeneously varied synaptic networks
Synaptic variablePropagation linearPropagation 2°Oscillation linearOscillation 2°
TRN1-TRN3 --0.115-
TRN3-TRN1 –0.088
TRN3-TRN2 –0.084–0.073--
TRN1=TRN2 –0.051–0.091--
TRN1=TRN3 –0.072---
TRN2=TRN3 -–0.1130.117-
TRN1-TC1 –0.075-0.6210.077
TRN1-TC2 0.6080.571–0.289–1.000
TRN2-TC2 –0.128–0.1960.3330.417
TRN2-TC3 1.0001.000–0.379–0.892
TRN3-TC3 –0.207–0.2391.0000.107
(TRN3-TRN2)2 -0.079--
(TRN1-TC2)2 -–0.245-0.189
(TRN2-TC2)2 -0.174-–0.093
(TRN2-TC3)2 -–0.472-0.278
(TRN3-TC3)2 -0.187-–0.146
TRN1-TRN2 × TRN1-TC2 -0.070--
TRN1-TRN3 × TRN3-TC3 ---0.215
TRN2-TRN1 × TRN1=TRN2 ---0.111
TRN2-TRN1 × TRN1-TC1 ---–0.186
TRN3-TRN1 × TRN1-TC1 ---–0.172
TRN3-TRN1 × TRN1-TC2 -–0.119--
TRN3-TRN1 × TRN2-TC3 -–0.096--
TRN3-TRN2 × TRN2-TC3 -–0.153--
TRN1=TRN2 × TRN2-TC3 ---–0.129
TRN1=TRN3 × TRN1-TC1 ---–0.114
TRN1=TRN3 × TRN3-TC3 -–0.079--
TRN1-TC1 × TRN1-TC2 ---0.634
TRN1-TC1 × TRN2-TC3 ---0.449
TRN1-TC2 × TRN2-TC2 -–0.166-0.361
TRN1-TC2 × TRN2-TC3 -0.753-–0.274
TRN1-TC2 × TRN3-TC3 -–0.106-0.669
TRN2-TC2 × TRN2-TC3 ---0.345
TRN2-TC2 × TRN3-TC3 ---–0.192
TRN2-TC3 × TRN3-TC3 -–0.124-0.399

  • The regressions include 1°, 2°, and interaction terms corresponding to the 14 variable synapses in the networks. Equal signs denote gap junctions. Linear regression for propagation, R2 = 0.742, RMSE = 0.069, p < 0.0001; 2° regression for propagation, R2 = 0.857, RMSE = 0.051, p < 0.0001; linear regression for oscillation, R2 = 0.253, RMSE = 0.131, p < 0.0001; 2° regression for oscillation, R2 = 0.388, RMSE = 0.118, p < 0.0001.