Table 1

Spontaneous swimming behavior of larval zebrafish at 5 dpf, comparing following hypoxia, to normoxia

TreatmentSwimming distance (mm)Velocity (mm/s)Rotation frequency (no/10 min)
Dark (4×)Light (3×)Dark (4×)Light (3×)Dark (4×)Light (3×)
Normoxia, n = 30, 21% pO2616.6 ± 48.3385.3 ± 38.31.4 ± 0.10.9 ± 0.160.4 ± 3.243.2 ± 3.4
Hypoxia 24–48 hpf, n = 30, 1% pO2399.5 ± 36.0197.2 ± 33.20.9 ± 0.10.4 ± 0.150.8 ± 4.631.6 ± 5.1
Hypoxia 48–72 hpf, n = 25, 3% pO2312.5 ± 28.8102.9 ± 18.80.7 ± 0.10.2 ± 0.143.3 ± 4.418.3 ± 2.6
Hypoxia 72–96 hpf, n = 30, 5% pO2391.0 ± 31.6190.7 ± 28.70.9 ± 0.10.4 ± 0.150.5 ± 34.127.9 ± 3.3
  • Behavioral paradigm used alternating light and dark exposures (see Materials and Methods for full description).