Table 2.

Mean (SE) number of h1a-only, arc-only, and double-stained cell nuclei as a function of brain area and drugs administered, 25 min apart, in Exp 2: saline–saline (n = 4), and cocaine (800 μg/kg)–saline (n = 6), cocaine (800 μg/kg)–cocaine (800 μg/kg; n = 6), cocaine (800 μg/kg)–heroin 100 μg/kg (n = 6), and cocaine (800 μg/kg)–heroin 200 μg/kg (n = 7)

NAcc coreNAcc shellDMSDLS
First saline
Second saline
h1a4.94 (0.66)4.44 (1.61)5.98 (2.18)8.5 (2.54)
arc2.38 (0.94)2.48 (0.75)1.98 (0.95)3.75 (1.59)
Double0.13 (0.07)0.38 (0.16)0.13 (0.07)0.13 (0.13)
First cocaine (800 μg/kg)
Second saline
h1a21.5 (4.44)8.67 (2.36)51.1 (7.99)65.1 (7.83)
arc4.25 (0.77)3.13 (0.68)5.58 (1.77)4.33 (0.95)
Double1.46 (0.25)1.67 (0.35)3.63 (0.43)4.46 (1.49)
First cocaine (800 μg/kg)
Second cocaine (800 μg/kg)
h1a20.54 (5.45)11.00 (2.87)42.17 (8.65)49.71 (7.5)
arc8.08 (0.59)5.13 (0.67)12.54 (1.99)15.33 (3.89)
Double5.46 (1.04)3.33 (0.77)14.17 (3.17)21.33 (5.19)
First cocaine (800 μg/kg)
Second heroin (100 μg/kg)
h1a20.33 (3.72)8.04 (2.36)58.67 (16.42)66.04 (11.36)
arc23.29 (9.55)18.92 (9.13)3.63 (0.70)3.04 (1.06)
Double5.00 (2.07)2.46 (0.87)4.17 (1.19)3.63 (0.96)
First cocaine (800 μg/kg)
Seconds heroin (200 μg/kg)
h1a18.96 (4.33)7.57 (1.75)50.68 (7.34) 56.46 (7.64) 
arc12.11 (1.53)12.61 (2.91)5.17 (0.74)4.32 (1.16)
Double3.14 (0.59)1.75 (0.49)3.11 (0.46)3.93 (0.93)