Table 2:

Summary statistics for startle threshold and PPI experiments

B6 miceFmr1 mice
ExperimentMean ± SEMMedianIQR
Q1–Q3
Mean ± SEMMedianIQR
Q1–Q3
p Value
Threshold (dB SPL)60329.0 ± 13.7289.0267–369380.1 ± 36.8312.5272–4120.2903
70387.0 ± 36.1320.0276–363349.0 ± 22.3306.0273–3600.0706
80391.0 ± 17.6326.0273–489457.3 ± 37.8320.5266–5390.8195
90633.8 ± 33.9586.0397–758731.3 ± 69.2502.5380–8690.5794
100887.0 ± 47.9815.5543–1187748.4 ± 50.5687.5450–9460.0583
1101001.9 ± 58.7954.0564–1297879.0 ± 54.6813.0546–10990.0828
120805.2 ± 53.2608.0400–1220880.7 ± 72.7706.0447–11460.7422
Gap detection (ISI)10.02 ± 0.03−0.0008−0.22 to 0.260.03 ± 0.030.06−0.11 to 0.270.5314
20.09 ± 0.030.080.13 to 0.320.08 ± 0.020.11−0.04 to 0.270.4421
50.24 ± 0.020.260.05–0.430.19 ± 0.020.230.03–0.380.1026
100.44 ± 0.020.490.35–0.620.33 ± 0.020.370.21–0.490.0153*
200.54 ± 0.020.590.41–0.690.38 ± 0.020.420.26–0.560.0011**
400.23 ± 0.020.240.10–0.410.18 ± 0.030.270.03–0.420.3753
800.10 ± 0.020.15−0.04 to 0.350.14 ± 0.020.210.04–0.340.3789
1600.15 ± 0.020.170.01–0.380.13 ± 0.020.19−0.01 to 0.360.6436
2400.15 ± 0.020.06−0.03 to 0.350.13 ± 0.020.19−0.02 to 0.340.7266
90° Speaker swap (ISI)1−0.05 ± 0.05−0.04−0.24 to 0.21−0.10 ± 0.04−0.05−0.35 to 0.150.5659
20.04 ± 0.040.10−0.16 to 0.27−0.04 ± 0.050.04−0.28 to 0.270.3390
50.12 ± 0.050.19−0.14 to 0.430.07 ± 0.050.12−0.13 to 0.310.5434
100.27 ± 0.030.260.13–0.440.11 ± 0.040.15−0.02 to 0.330.0823
200.35 ± 0.030.390.18–0.560.13 ± 0.050.19−0.05 to 0.420.0136*
300.31 ± 0.040.370.12–0.540.12 ± 0.050.16−0.13 to 0.410.0388*
400.26 ± 0.030.280.10–0.460.12 ± 0.050.18−0.09 to 0.380.1329
800.32 ± 0.030.360.23–0.510.16 ± 0.040.24−0.06 to 0.410.0809
1000.27 ± 0.040.320.09–0.480.20 ± 0.030.190.03–0.430.4565
1500.37 ± 0.030.420.19–0.560.23 ± 0.030.270.06–0.450.1400
3000.25 ± 0.030.250.11–0.430.12 ± 0.040.15−0.06 to 0.350.1571
Speaker swap (angle)7.5°0.01 ± 0.020.008−0.21 to 0.22−0.04 ± 0.030.06−0.12 to 0.210.4647
15°0.04 ± 0.020.03−0.14 to 0.260.06 ± 0.020.100.07 to 0.290.6043
30°0.005 ± 0.030.04−0.18 to 0.230.02 ± 0.020.08−0.12 to 0.260.6542
45°0.10 ± 0.030.17−0.14 to 0.360.13 ± 0.020.170.010–0.370.3635
90°0.22 ± 0.020.240.08–0.400.12 ± 0.020.18−0.01 to 0.370.0228*
Threshold SRM (dB attenuation)90.40 ± 0.020.420.25–0.560.27 ± 0.030.300.19–0.440.0309*
120.48 ± 0.020.550.33–0.650.31 ± 0.030.340.23–0.470.0067**
150.49 ± 0.020.560.37–0.650.34 ± 0.020.360.23–0.510.0153*
180.32 ± 0.030.320.21–0.470.29 ± 0.020.320.18–0.460.6152
210.18 ± 0.030.210.07–0.380.17 ± 0.040.27−0.03 to 0.390.7820
240.05 ± 0.030.100.09 to 0.250.09 ± 0.030.08−0.11 to 0.330.5292
27−0.04 ± 0.040.04−0.23 to 0.190.05 ± 0.040.12−0.11 to 0.320.1145
SRM 15 dB attenuation
(angle)
7.5°0.42 ± 0.030.460.23–0.610.34 ± 0.030.400.23–0.480.2315
15°0.38 ± 0.030.350.20–0.610.30 ± 0.030.330.17–0.490.2133
22.5°0.36 ± 0.030.370.22–0.580.33 ± 0.030.400.17–0.490.6620
30°0.34 ± 0.030.400.19–0.570.31 ± 0.020.350.21–0.470.6156
45°0.41 ± 0.030.450.23–0.610.31 ± 0.030.350.15–0.470.1220
90°0.42 ± 0.030.490.27–0.640.21 ± 0.040.310.04–0.430.0030**
SRM 24 dB attenuation
(angle)
7.5°−0.02 ± 0.04−0.002−0.24 to 0.190.07 ± 0.040.11−0.09 to 0.350.1804
15°−0.05 ± 0.030.07−0.16 to 0.280.06 ± 0.040.13−0.07 to 0.280.8865
22.5°−0.006 ± 0.030.009−0.19 to 0.18−0.02 ± 0.050.11−0.16 to 0.300.8580
30°0.02 ± 0.04 0.07−0.20 to 0.280.04 ± 0.04 0.08−0.11 to 0.310.7420
45°0.03 ± 0.040.13−0.20 to 0.280.04 ± 0.040.09−0.11 to 0.320.8239
90°0.18 ± 0.030.240.06–0.380.18 ± 0.030.23−0.03 to 0.430.9639
  • Values in bold indicate a PPI not significantly different from zero.