Table 1:

Statistical summary

IdentifierShapiro–Wilk
(α = 0.05)
Test95% CI
aNormalRaldh2 mRNA puncta/mm; unpaired t test between genotypes at P2, one-tailed–2521 to –1732
bNormalPDGFRβ+ structures/mm2; unpaired t test between genotypes at P14, two-tailed–42.62 to 16.82
cNormalLaminin+ structures/mm2; unpaired t test between genotypes at P14, two-tailed–94.79 to 21.25
dNormalPDGFRβ+Laminin+/Laminin+ structures %, unpaired t test between genotypes at P14, two-tailed–2.765 to 21.69
eNormalOLIG2+ cells/mm2; one-way ANOVA with Sidak’s test between genotypes at individual time points
P24.080 to 494.0
P780.47 to 547.6
P14126.6 to 593.7
P21108.9 to 681.0
fNormalOLIG2+ cells/mm2; unpaired t test within control genotype between individual time points P2 vs P21, one-tailed–441.0 to 282.2
gNormalOLIG2+ cells/mm2; unpaired t test within cKO genotype between individual time points P2 vs P21, one-tailed–490.0 to 39.44
hNormalPDGFRα+OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points
iNormalPDGFRα+OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons within control genotype at individual time points
P2 vs P7–121.2 to 55.21
P7 vs P14–184.2 to –16.61
P14 vs P218.089 to 221.1
P2 vs P21–224.6 to –42.19
jNormalPDGFRα+OLIG2+/OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points
P2–26.25 to –9.080
P7–21.13 to –3.288
P14–20.19 to –1.376
P21–12.09 to 6.720
kNormalCC1+OLIG2+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points
P7–21.38 to 87.30
P1432.72 to 141.4
P2149.38 to 158.1
lNormalCC1+OLIG2+ cells/OLIG2+ cells %; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points
P142.156 to 20.30
P211.024 to 19.16
mNormalPLP+ area (mm2); one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points
P7–18.20 to 107.8
P1430.06 to 138.5
P2125.44 to 139.2
P12069.15 to 211.4
nNormalTUNEL+ cells/mm2; unpaired t test within control genotype between individual time points P2 vs P7, one-tailed–41.86 to –15.94
oNormalTUNEL+ cells/mm2; unpaired t test within cKO genotype between individual time points P2 vs P7, one-tailed–18.13 to 4.871
pNormalTUNEL+ cells/mm2; one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points
P2–9.109 to 16.03
P7–30.05 to –7.565
P140.9951 to 10.17
qNormalIBA1+ cells/mm2 one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points
P7–46.17 to 51.34
P14–92.57 to 4.941
P21–37.76 to 67.56
rNormalGli1 mRNA puncta/mm2; unpaired t test between genotypes at P2, one-tailed–15,405 to –2876
sNormalGli1 mRNA puncta/cell; n= number of cells, unpaired t test between genotypes at P2, one-tailed–3.692 to –1.703
tNormalGli1+Olig2+ cells/mm2; unpaired t test between genotypes at P2, one-tailed–53.01 to –33.57
uNormalÄGFAP+ area (mm2); one-way ANOVA with Sidak’s test for multiple comparisons between genotypes at individual time points
P20.8137 to 7.880
P74.695 to 12.44
P146.558 to 14.30
P213.638 to 11.38
vNormalSATB2+ cells/mm2; unpaired t test between genotypes at P2, one-tailed159.9 to 1991
wNormalCTIP2+ cells/mm2; unpaired t test between genotypes at P2, two-tailed–172.6 to –68.02
xNormalTBR1+ cells/mm2; unpaired t test between genotypes at P2, two-tailed–1407 to –439.5
yNormalCortical thickness (um); unpaired t test between genotypes at P2, two-tailed–234.6 to 26.12