Intrinsic properties of PVT neurons following saline or morphine treatment during the light or dark cycle
| Saline light | Morphine light | Saline dark | Morphine dark | |
|---|---|---|---|---|
| RMP (mV) | –59.36 ± 0.90 (33) | –54.89 ± 0.95 (32)** | –51.38 ± 1.04 (33)**^ | –50.77 ± 0.64 (36)**^^ |
| Capacitance (pF) | 56.57 ± 3.61 (23) | 56.79 ± 3.48 (19) | 64.27 ± 4.49 (22) | 62.58 ± 4.25 (24) |
| Membrane resistance (MΩ) | 562.4 ± 54.2 (23) | 563.0 ± 75.79 (19) | 1149 ± 129 (22)**^^ | 1193 ± 166.2 (24)**^^ |
| Voltage sag (mV) | 4.09 ± 0.40 (15) | 4.85 ± 1.08 (15) | 6.69 ± 1.17 (16)* | 6.23 ± 1.82 (19) |
Passive properties were compared across treatment groups using independent samples t tests. Mean ± SEM; number of cells (n); *significantly different from saline light; ^signifcantly different from morphine light; * or ^p < 0.05, ** or ^^p < 0.01. RMP, resting membrane potential.