CL | Gene | # leading edge subsets | mean r | Associated cognitive function | |||
---|---|---|---|---|---|---|---|
Mems | Memw | Mots | Motw | ||||
Memory subcortical + | CDK5 | 27 | 0.26 | Y | Y | ||
NLGN1 | 26 | 0.51 | Y | ||||
UNC13B | 26 | 0.38 | Y | ||||
RAB3A | 25 | 0.40 | Y | Y | |||
STX1A | 24 | 0.57 | Y | ||||
SYT12 | 23 | 0.44 | Y | ||||
STX1B | 22 | 0.45 | Y | ||||
SNCA | 21 | 0.44 | Y | Y | |||
SYT1 | 21 | 0.39 | Y | Y | |||
UNC13A | 20 | 0.46 | Y | Y | |||
Memory subcortical – | RPL34 | 8 | –0.54 | Y | |||
RPS12 | 8 | –0.49 | |||||
RPS13 | 8 | –0.47 | Y | ||||
RPS15A | 8 | –0.44 | Y | ||||
RPS29 | 8 | –0.44 | |||||
RPL11 | 8 | –0.44 | Y | ||||
RPL37A | 8 | –0.44 | |||||
RPL10 | 8 | –0.44 | Y | ||||
RPS25 | 8 | –0.44 | Y | ||||
RPS27 | 8 | –0.43 | Y |
See Table 2 for notation, Extended Data Table 4-1 for the literature review supporting the subcortical gene-cognition associations, and Extended Data Table 4-2 for the complete LEA output for subcortical analyses.