Table 2.

Results of PantherDB analysis for the comparison between sham and retrieval groups

PANTHER GO-Slim pathwaysOver/UnderFold enrichmentRaw
p value
FDR
(q value)
Cellular ComponentPostsynaptic membrane (GO:0045211)+14.719.98E-097.99E-08
Neuromuscular junction (GO:0031594)+11.033.83E-031.29E-02
Proton-transporting ATP synthase complex (GO:0045259)+9.81.20E-034.51E-03
Synapse (GO:0045202)+8.311.24E-127.96E-11
Mitochondrial inner membrane (GO:0005743)+7.14.77E-095.08E-08
Dendrite (GO:0030425)+7.081.49E-081.06E-07
SNARE complex (GO:0031201)+6.065.75E-031.84E-02
Neuron projection (GO:0043005)+5.332.61E-115.57E-10
Cell junction (GO:0030054)+5.055.70E-052.60E-04
Axon (GO:0030424)+4.681.31E-023.98E-02
Cell projection (GO:0042995)+3.757.41E-096.77E-08
Protein complex (GO:0043234)+2.318.91E-122.85E-10
Cytoskeleton (GO:0005856)+2.25.35E-042.14E-03
Membrane (GO:0016020)+1.991.14E-091.46E-08
Integral to membrane (GO:0016021)+1.875.15E-042.20E-03
Macromolecular complex (GO:0032991)+1.792.02E-071.17E-06
Cytoplasm (GO:0005737)+1.765.38E-108.61E-09
Plasma membrane (GO:0005886)+1.591.62E-035.77E-03
Cell part (GO:0044464)+1.441.96E-071.25E-06
Intracellular (GO:0005622)+1.372.18E-051.07E-04
Biological Process*Growth (GO:0040007)+19.31.01E-038.82E-03
Asymmetric protein localization (GO:0008105)+15.441.70E-031.34E-02
Oxidative phosphorylation (GO:0006119)+10.892.67E-089.31E-07
Pyrimidine nucleobase metabolic process (GO:0006206)+8.35.69E-046.31E-03
JNK cascade (GO:0007254)+8.046.47E-046.32E-03
Respiratory electron transport chain (GO:0022904)+7.353.03E-091.48E-07
Generation of precursor metabolites and energy (GO:0006091)+6.031.52E-113.72E-09
Neuron-neuron synaptic transmission (GO:0007270)+5.722.13E-053.25E-04
Purine nucleobase metabolic process (GO:0006144)+5.634.04E-044.93E-03
Glycolysis (GO:0006096)+5.511.15E-039.39E-03
Mitochondrial transport (GO:0006839)+5.483.06E-031.86E-02
Neurotransmitter secretion (GO:0007269)+4.981.46E-041.98E-03
Cation transport (GO:0006812)+4.241.89E-031.44E-02
Calcium-mediated signaling (GO:0019722)+4.142.14E-031.45E-02
Mitochondrion organization (GO:0007005)+42.56E-031.65E-02
Synaptic transmission (GO:0007268)+3.995.54E-104.51E-08
Anatomical structure morphogenesis (GO:0009653)+3.686.22E-046.60E-03
Protein targeting (GO:0006605)+3.475.29E-046.15E-03
Ion transport (GO:0006811)+2.871.82E-052.96E-04
Cell-cell signaling (GO:0007267)+2.863.92E-079.58E-06
Molecular Function*Glutamate receptor activity (GO:0008066)+11.33.82E-079.12E-06
Nucleotide kinase activity (GO:0019201)+10.291.32E-051.94E-04
SNAP receptor activity (GO:0005484)+7.353.07E-032.66E-02
Hydrogen ion transmembrane transporter activity (GO:0015078)+7.054.00E-068.48E-05
Carbohydrate kinase activity (GO:0019200)+6.644.27E-033.26E-02
Anion channel activity (GO:0005253)+5.253.61E-032.87E-02
Ligand-gated ion channel activity (GO:0015276)+5.074.31E-068.24E-05
Voltage-gated ion channel activity (GO:0005244)+4.142.14E-032.27E-02
Ion channel activity (GO:0005216)+4.065.90E-093.76E-07
Cation channel activity (GO:0005261)+3.582.49E-032.51E-02
Microtubule binding (GO:0008017)+3.45.95E-034.37E-02
Small GTPase regulator activity (GO:0005083)+3.391.12E-031.34E-02
Oxidoreductase activity (GO:0016491)+35.89E-081.88E-06
Kinase activity (GO:0016301)+2.792.71E-077.39E-06
Calcium ion binding (GO:0005509)+2.792.80E-032.54E-02
  • * See Extended Data Table 2-1 for all GO-Slim pathway terms.