Table 1.

Results of PantherDB analysis for the comparison between sham and acquisition groups

PANTHER GO-Slim pathwaysOver/UnderFold enrichmentRaw
p value
FDR
(q value)
Cellular ComponentPostsynaptic membrane (GO:0045211)+30.259.68E-113.10E-09
Neuromuscular junction (GO:0031594)+25.213.67E-042.14E-03
Synapse (GO:0045202)+12.672.09E-111.34E-09
Dendrite (GO:0030425)+9.717.15E-079.15E-06
Neuron projection (GO:0043005)+7.038.27E-091.77E-07
Cell junction (GO:0030054)+6.923.10E-041.98E-03
Cell projection (GO:0042995)+4.93.05E-074.88E-06
Integral to membrane (GO:0016021)+2.693.03E-052.42E-04
Plasma membrane (GO:0005886)+2.434.05E-063.70E-05
Cytoskeleton (GO:0005856)+2.319.41E-034.63E-02
Membrane (GO:0016020)+2.143.70E-063.94E-05
Protein complex (GO:0043234)+2.10.00017.14E-04
Biological ProcessGrowth (GO:0040007)+44.129.25E-052.51E-03
Asymmetric protein localization (GO:0008105)+35.291.58E-043.86E-03
Muscle organ development (GO:0007517)+26.143.03E-071.85E-05
Neuron-neuron synaptic transmission (GO:0007270)+13.071.27E-081.55E-06
Pyrimidine nucleobase metabolic process (GO:0006206)+11.392.91E-033.55E-02
Synaptic transmission (GO:0007268)+6.384.01E-119.80E-09
Ion transport (GO:0006811)+4.482.13E-068.66E-05
Cell-cell signaling (GO:0007267)+4.432.12E-081.72E-06
Cytoskeleton organization (GO:0007010)+3.221.35E-032.20E-02
Protein localization (GO:0008104)+2.881.20E-032.08E-02
Transport (GO:0006810)+2.354.58E-061.60E-04
Localization (GO:0051179)+2.349.21E-074.50E-05
Neurological system process (GO:0050877)+2.113.25E-047.21E-03
System process (GO:0003008)+2.054.42E-048.30E-03
Phosphate-containing compound metabolic process (GO:0006796)+1.941.45E-032.09E-02
Cellular component organization (GO:0016043)+1.762.71E-033.48E-02
Cell communication (GO:0007154)+1.553.25E-033.77E-02
Sensory perception of smell (GO:0007608)-<0.012.15E-032.92E-02
Sensory perception of chemical stimulus (GO:0007606)-<0.011.44E-032.19E-02
Sensory perception (GO:0007600)-<0.010.0004260.00866
Molecular FunctionGlutamate receptor activity (GO:0008066)+22.967.33E-093.50E-07
Nucleotide kinase activity (GO:0019201)+20.171.16E-063.70E-05
Voltage-gated calcium channel activity (GO:0005245)+13.072.02E-033.51E-02
Ligand-gated ion channel activity (GO:0015276)+9.83.71E-081.42E-06
Voltage-gated ion channel activity (GO:0005244)+8.111.37E-042.91E-03
Voltage-gated potassium channel activity (GO:0005249)+7.592.34E-033.44E-02
Ion channel activity (GO:0005216)+7.131.86E-113.56E-09
Cation channel activity (GO:0005261)+5.123.51E-034.19E-02
Small GTPase regulator activity (GO:0005083)+4.642.25E-033.59E-02
Transmembrane transporter activity (GO:0022857)+3.84.03E-093.84E-07
Transporter activity (GO:0005215)+3.544.84E-093.08E-07
GTPase activity (GO:0003924)+3.131.67E-033.19E-02
Kinase activity (GO:0016301)+2.522.41E-033.29E-02
Pyrophosphatase activity (GO:0016462)+2.383.84E-034.31E-02
Catalytic activity (GO:0003824)+1.743.98E-061.08E-04
Protein binding (GO:0005515)+1.640.003130.0399
  • * See Extended Data Table 1-1 for all Reactome pathway terms identified from the comparison between sham and acquisition groups.