Details of analyzed AD mouse model studies
| Model types | Mouse model(s) | Study (dataset) | Phase(s) | Samples | Platform | Genes | M/F |
|---|---|---|---|---|---|---|---|
| Amyloid | Tg2576 | GSE36237 (Kleiman et al., 2010) | Early | 16 (8/8) | GPL1261 | 18118 | 0/16 |
| GSE1556 (Stein et al., 2004) | Late | 4 (2/2) | GPL81 | 8237 | 0/4 | ||
| GSE15056 (Pereson et al., 2009) | Late | 4 (2/2) | GPL7202 | 19459 | 0/4 | ||
| 5xFAD | GSE52022 (Noh et al., 2014) | Late | 4 (2/2) | GPL1261 | 18118 | 0/4 | |
| GSE50521 (Paesler et al., 2015) | Late | 12 (6/6) | GPL6096 | 16743 | 8/4 | ||
| J20 | GSE14499 (Nagahara et al., 2009) | Late | 6 (2/4) | GPL1261 | 18118 | 2/4 | |
| Amyloid TAU | TAS10, TPM, TASTPM TAU | GSE64398 (Cummings et al., 2015; Matarin et al., 2015) | Early, late | 108(39/69) | GPL6885 | 17339 | 108/0 |
| TAU | rTg4510 | GSE53480 (Polito et al., 2014) | Late | 8 (4/4) | GPL1261 | 18118 | 5/3 |
| KO | Aplp2 KO, App KO, App/Aplp2 double-conditional KO (NdC-KO) | GSE48622 (Li et al., 2010) | Early | 16 (4/12) | GPL1261 | 18118 | 16/0 |
| Other | Anti-NGF AD11 (AD11) | GSE63617 (D’Onofrio et al., 2011) | Early, late | 30 (15/15) | GPL7042, GPL7202 | 19459 | 0/30 |
Number of control and case samples are shown in parentheses (control/case). Genes refer to the number of unique genes mapped. M/F: number of male and female samples. Amyloid: amyloid transgenic models; TAU: TAU transgenic models.