Table 2

: Expression of additional clock (Per1, Clock) and inflammatory (Iba1, Mhc II) genes at 2 d postsurgery in the lesion epicenter and lumbar spinal cord (data only for genes not shown in figures)

	Female				Male				Significant differences
	ZT6		ZT18		ZT6		ZT18		Significant differences
Gene	Sham	SCI	Sham	SCI	Sham	SCI	Sham	SCI	Main effect	Interactions
Per1
Lesion Lumbar	1.00 ± 0.10 1.00 ± 0.05	0.39 ± 0.06 1.04 ± 0.29	1.19 ± 0.07 0.97 ± 0.09	0.23 ± 0.03 0.70 ± 0.03	1.01 ± 0.17 0.78 ± 0.08	0.35 ± 0.06 0.57 ± 0.07	2.01 ± 0.57 0.84 ± 0.12	0.34 ± 0.01 0.50 ± 0.02	SCI: ZT6 + 18 SCI, sex	Sham × ZT N.S.
Clock
Lesion Lumbar	1.00 ± 0.16 1.00 ± 0.03	0.32 ± 0.03 0.71 ± 0.10	1.21 ± 0.18 1.07 ± 0.06	0.27 ± 0.04 0.64 ± 0.04	0.90 ± 0.18 0.94 ± 0.07	0.36 ± 0.09 0.53 ± 0.07	1.56 ± 0.33 0.83 ± 0.08	0.29 ± 0.03 0.45 ± 0.04	SCI SCI	Sham × ZT Sham × ZT
Iba1
Lesion Lumbar	1.00 ± 0.21 1.00 ± 0.07	0.75 ± 0.03 1.36 ± 0.04	0.86 ± 0.08 0.96 ± 0.08	0.93 ± 0.09 1.38 ± 0.13	0.69 ± 0.09 1.32 ± 0.05	0.41 ± 0.07 2.06 ± 0.45	0.59 ± 0.04 1.23 ± 0.12	0.78 ± 0.14 1.54 ± 0.18	Sex N.S.	SCI × ZT;ZT6 × inj. N.S.
Mhc II
Lesion Lumbar	1.00 ± 0.17 1.00 ± 0.19	0.21 ± 0.05 0.50 ± 0.05	0.82 ± 0.09 0.54 ± 0.21	0.21 ± 0.03 0.54 ± 0.18	0.65 ± 0.14 1.59 ± 0.38	0.23 ± 0.05 0.86 ± 0.14	0.79 ± 0.14 1.09 ± 0.30	0.22 ± 0.05 0.54 ± 0.11	SCI SCI, sex	N.S. N.S.

For statistical comparisons (far right column): SCI, significant main effect of SCI vs sham; ZT, significant main effect of time (ZT6 vs ZT18); sex, significant main effect of sex; Sham × ZT, significant interaction between sham and ZT; N.S., no significant difference.