Table 5.

Mean values for amplitude of glutamatergic sEPSCs, mEPSCs, and mEPSC rise time at baseline and during acute nicotine challenge

BaselineAcute nicotine challenge
sEPSC amplitude (pA)Control:
P1–P2P3–P5DNE:P1–P2P3–P5–15.2 ± 2.7–15.5 ± 2.3 –18.5 ± 7.4–16.4 ± 2.8–16.0 ± 3.2–15.7 ± 3.9 –18.3 ± 8.9–14.8 ± 2.9
mEPSC amplitude (pA)Control:
P1–P2P3–P5DNE:P1–P2P3–P5–16.2 ± 2.6–14.9 ± 3.0 –16.0 ± 2.9–17.5 ± 1.9–14.6 ± 2.6–16.3 ± 3.7 –15.6 ± 3.8–17.4 ± 1.9
mEPSC rise time (ms)Control:
P1–P2P3–P5DNE:P1–P2P3–P5    2.1 ± 0.2 2.0 ± 0.1  2.1 ± 0.2 1.8 ± 0.1    2.1 ± 0.2 2.2 ± 0.1  2.0 ± 0.1 2.0 ± 0.1
  • There were no significant differences in any of these variables.