Table 2:

Summary of statistical analysis used in each experiment

ExperimentTestp ValueStatistical valuePost hoc testPairwise comparisonp Value
Figure 2C Num. BrdU+ (age × Anat. location)Two-way RM ANOVAAnat. Location = 0.0014Age < 0.0001Interaction = 0.003Anat. Location, F(1,12) = 17.19Age F(1,12) = 36.21Interaction F(1,12) = 13.28Bonferroni’s correctionVentral: P7 vs P25Dorsal: P7 vs P250.0002<0.0001
P7: dorsal vs ventralP25: dorsal vs ventraln.s.0.0005
Figure 3ENum. BrdU+ at P25(Anat. location × time point)Two-way RM ANOVAAnat. Location < 0.0001Time point = n.s.Interaction = n.s.Anat. Location F(1,8) = 134.7Time point F(3,8) = 1.947Interaction F(3,8) = 1.133Bonferroni’s correctionDorsal vs ventral:DPI 1DPI 3DPI 5DPI 7    0.00950.00060.00080.0019
Figure 3FNum. Ki67+ at P25 (Anat. location × time point)Two-way RM ANOVAAnat. Location < 0.0001Time point = 0.004Interaction = n.s.Anat. Location F(1,8) = 149.4Time point F(3,8) = 10.06Interaction F(3,8) = 2.666Bonferroni’s correctionDorsal vs ventral:DPI 1DPI 3DPI 5DPI 7    0.00140.00010.00890.0018
Ventral:DPI 3 vs DPI 5    0.0154
Figure 3GVentral Num. BrdU+ vs Ki67+ (marker × time point)Two-way RM ANOVAMarker = n.s.Time point = n.s.Interaction = n.s.Marker F(1,8) = 0.8985Time point F(3,8) = 2.71Interaction F(3,8) = 3.345
Figure 4AMigration P25(Anat. location × time point)Two-way RM ANOVAAnat. Location = 0.0002Time point < 0.0001Interaction = n.s.Anat. Location F(1,8) = 43.85Time point F(3,8) = 51.44Interaction F(3,8) = 3.477Bonferroni’s correctionDorsal vs ventral:DPI 3DPI 8    0.02120.0026
Dorsal:DPI 1 vs DPI 3Ventral:DPI 1 vs DPI 3DPI 5 vs DPI 8    0.027 <0.00010.0025
Figure 4BMigration P25(Anat. location × time point)Two-way RM ANOVAAnat. Location = 0.0001Time point = 0.0103Interaction = 0.106Anat. Location F(1,8) = 50.03Time point F(3,8) = 7.511Interaction F(3,8) = 2.826Bonferroni’s correctionDorsal vs ventral:DPI 4DPI 6DPI 8    0.01440.02540.0033
Figure 4CVentral migration P25 (time point)One-way ANOVA<0.0001F(5,12) = 30.28Bonferroni’s correctionn.s. individual comparisons
Figure 4EOSNs maturation (marker × time point)Two-way RM ANOVABrdU/marker = 0.0067Time point < 0.0001Interaction < 0.0001Marker F(2,24) = 6.22Time point F(5,12) = 32.45Interaction F(10,24) = 13.85Bonferroni’s correctionMarker dynamic:GAP 43:DPI 3 vs DPI 5DPI 10 vs DPI 12AC 3:DPI 5 vs DPI 8DPI 8 vs DPI 10OMP:DPI 8 vs DPI 10DPI 10 vs DPI 12        0.02340.0011 0.040.0168 0.01510.00031
Differential marker expression at each time point:DPI 5:GAP 43 vs AC 3GAP 43 vs OMPDPI 8:OMP vs AC 3OMP vs GAP 43DPI 10:AC 3 vs OMPDPI 12:GAP 43 vs AC 3GAP 43 vs OMP                0.0004<0.0001  0.0050.0075 0.0055 <0.0001<0.0001
  • Anat. location, Anatomic location; num., number; RM, repeated measures; n.s., not significant.