Description | Type of test | Sample size | Statistical data |
---|---|---|---|

Figure 1: Comparison of learning curves | |||

Male control groups | RM ANOVA | WT/Reg: n = 3WT/Val: n = 3Nes-TK/Reg: n = 5 | Group:F = 3.84p = 0.0677 |

Female control groups | RM ANOVA | WT/Reg: n = 3WT/Val: n = 1Nes-TK/Reg: n = 2 | Group:F = 0.51p = 0.6454 |

Male vs female controls | RM ANOVA | Male: n = 11Female: n = 6 | Group:F = 0.63p = 0.6346 |

Male; Con vs Exp | RM ANOVA | Con: n = 11Exp: n = 13 | Group:F = 15.2p = 0.0008Interaction: F = 1.837p = 0.0487 |

Male; Con vs Exp All sessions | Unpaired t tests | Con: n = 11Exp: n = 13 | H1: p = 0.06H2: p = 0.24T1: p = 0.022T2: p = 0.0071T3: p = 0.0011T4: p = 0.029T5: p = 0.018T6: p = 0.0017T7: p = 0.0087T8: p = 0.0045T9: p = 0.034T10: p = 0.062 |

Female; Con vs Exp | RM ANOVA | Con: n = 6Exp: n = 5 | Group:F = 0.89p = 0.3696 |

Figure 2: Comparing number of DCX^{+} cells | |||

Male; Con vs Exp | Unpaired t test | Con: n = 11Exp: n = 13 | p = 0.0011 |

Female; Con vs Exp | Unpaired t test | Con: n = 6Exp: n = 5 | p = 0.0947 |

Figure 3: Correlation between learning and number of DCX^{+} cells | |||

Male; DCX vs average CRs | Pearson’s correlation | n = 24 | r = 0.574p = 0.0027 |

Male; DCX vs trials to 6 CRs of 10 trials | Pearson’s correlation | n = 24 | r = −0.519p = 0.0121 |

Female; DCX vs average CRs | Pearson’s correlation | n = 11 | r = −0.025p = 0.943 |

Female; DCX vs trials to 6 CRs of 10 trials | Pearson’s correlation | n = 11 | r = 0.102p = 0.77 |

All datasets are assumed to have normal distribution. Con, control; Exp, experimental; Reg, regular chow; Val, valganciclovir chow; RM, repeated measures.