List of statistical tests
| Reference number | Data structure | Parameter tested | Type of test | p value | Figure |
|---|---|---|---|---|---|
| 1 | Two independent samples: ketamine-terminal (n = 57) isoflurane-terminal (n = 351) | Single-unit threshold (relative to age-matched CAP audiograms) | Mann–Whitney | <0.001 | 2A |
| 2 | Two independent samples: ketamine-terminal (n = 5) isoflurane-terminal (n = 49) | Single-unit threshold (relative to age-matched CAP audiograms) CF <1.5 kHz | Mann–Whitney | 0.004 | 2B |
| 3 | Two independent samples: ketamine-terminal (n = 14) isoflurane-terminal (n = 76) | Single-unit threshold (relative to age-matched CAP audiograms) CF 1.5–3 kHz | Mann–Whitney | <0.001 | 2B |
| 4 | Two independent samples: ketamine-terminal (n = 20) isoflurane-terminal (n = 89) | Single-unit threshold (relative to age-matched CAP audiograms) CF 3–4.5 kHz | Mann–Whitney | <0.001 | 2B |
| 5 | Two independent samples: ketamine-terminal (n = 17) isoflurane-terminal (n = 86) | Single-unit threshold (relative to age-matched CAP audiograms) CF 4.5–6 kHz | Mann–Whitney | <0.001 | 2B |
| 6 | Five independent samples (age groups): P11 to P14 (n = 99) P17 (n = 35) P21 to 32 (n = 87) P35 to P40 (n = 17) P51 to P86 (n = 38) | Single-unit spontaneous discharge rate | Kruskal–Wallis | <0.001 | |
| 7 | Two independent samples: P11 to P14 (n = 99) P17 (n = 35) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | <0.001 | |
| 8 | Two independent samples: P11to P14 (n = 99) P21 to P32 (n = 87) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.001 | |
| 9 | Two independent samples: P11 to P14 (n = 99) P35 to P40 (n = 17) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.003 | |
| 10 | Two independent samples: P11 to P14 (n = 99) P51 to P86 (n = 38) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.002 | |
| 11 | Two independent samples: P17 (n = 35) P21 to P32 (n = 87) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.346 | |
| 12 | Two independent samples: P17 (n = 35) P35 to P40 (n = 17) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.992 | |
| 13 | Two independent samples: P17 (n = 35) P51 to P86 (n = 38) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.614 | |
| 14 | Two independent samples: P21 to 32 (n = 87) P35 to P40 (n = 17) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.467 | |
| 15 | Two independent samples: P21 to P32 (n = 87) P51 to P86 (n = 38) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.718 | |
| 16 | Two independent samples: P35 to P40 (n = 17) P51 to P86 (n = 38) | Single-unit spontaneous discharge rate | Mann–Whitney Bonferroni corrected | 0.826 | |
| 17 | Two independent samples: ketamine-terminal (n = 56) isoflurane-terminal (n = 260) | Single-unit spontaneous discharge rate, all ages ≥P17 | Mann–Whitney | 0.005 | 4A |
| 18 | Two independent samples: ketamine-terminal (n = 5) isoflurane-terminal (n = 29) | Single-unit spontaneous discharge rate, all ages ≥P17 and CF <1.5 kHz | Mann–Whitney | 0.575 | 4B |
| 19 | Two independent samples: ketamine-terminal (n = 14) isoflurane-terminal (n = 30) | Single-unit spontaneous discharge rate, all ages ≥P17 and CF 1.5–3 kHz | Mann–Whitney | 0.035 | 4B |
| 20 | Two independent samples: ketamine-terminal (n = 19) isoflurane-terminal (n = 62) | Single-unit spontaneous discharge rate, all ages ≥P17 and CF 3–4.5 kHz | Mann–Whitney | 0.858 | 4B |
| 21 | Two independent samples: ketamine-terminal (n = 17) isoflurane-terminal (n = 88) | Single-unit spontaneous discharge rate, all ages ≥P17 and CF 4.5–6 kHz | Mann–Whitney | 0.264 | 4B |
| 22 | Two independent samples: ketamine-terminal (n = 53) isoflurane-terminal (n = 327) | Single-unit Q10 dB | Mann–Whitney | 0.098 | |
| 23 | Three dependent samples (n = 24): ketamine-ABR isoflurane-ABR sevoflurane-ABR | ABR threshold | Friedman | <0.001 | 5 |
| 24 | Two dependent samples (n = 24): ketamine-ABR isoflurane-ABR | ABR threshold | Wilcoxon Bonferroni corrected | <0.001 | 5 |
| 25 | Two dependent samples (n = 24): ketamine-ABR sevoflurane-ABR | ABR threshold | Wilcoxon Bonferroni corrected | <0.001 | 5 |
| 26 | Two dependent samples (n = 24): isoflurane-ABR sevoflurane-ABR | ABR threshold | Wilcoxon Bonferroni corrected | 0.076 | 5 |
| 27 | Six independent samples: 1/2/4/6/8/10 kHz (n = 4 each) | ABR threshold difference: isoflurane-ABR−ketamine-ABR condition | Kruskal–Wallis | 0.406 | 5B |
| 28 | Six independent samples: 1/2/4/6/8/10 kHz (n = 4 each) | ABR threshold difference: sevoflurane-ABR−ketamine-ABR condition | Kruskal–Wallis | 0.472 | 5B |
| 29 | Three dependent samples (n = 16): ketamine-ABR isoflurane-ABR sevoflurane-ABR | ABR amplitudes 10 dB above threshold | Friedman | 0.068 | |
| 30 | Three dependent samples (n = 16): ketamine-ABR isoflurane-ABR sevoflurane-ABR | ABR latencies 10 dB above threshold | Friedman | 0.646 | |
| 31 | Two dependent samples (n = 24): ABR-terminal, ketamine ABR-terminal, ketamine + oxygen | ABR threshold | Wilcoxon | 0.163 | |
| 32 | Three dependent samples (n = 11): ABR-terminal, 1% isoflurane ABR-terminal, 2% isoflurane ABR-terminal, 1% isoflurane repeat | ABR threshold | Friedman | <0.001 | 6A |
| 33 | Two dependent samples (n = 11): ABR-terminal, 1% isoflurane ABR-terminal, 2% isoflurane | ABR threshold | Wilcoxon Bonferroni corrected | 0.003 | 6A |
| 34 | Two dependent samples (n = 11): ABR-terminal, 2% isoflurane ABR-terminal, 1% isoflurane repeat | ABR threshold | Wilcoxon Bonferroni corrected | 0.003 | 6A |
| 35 | Two dependent samples (n = 11): ABR-terminal, 1% isoflurane ABR-terminal, 1% isoflurane repeat | ABR threshold | Wilcoxon Bonferroni corrected | 0.262 | 6A |
| 36 | Two dependent samples (n = 24): ABR-terminal, ketamine + oxygen ABR-terminal, 1% isoflurane | ABR threshold | Wilcoxon | 0.004 | |
| 37 | Two dependent samples (n = 24): isoflurane-ABR (normalized compared with ketamine) ABR-terminal, 1% isoflurane (normalized compared with ketamine) | ABR threshold | Wilcoxon | <0.001 | |
Column 1 shows the serial number used to refer to specific tests throughout the article. Column 2 defines the samples, and column 3 the tested parameter. Column 4 lists the specific nonparametric test used, and column 5 shows the resulting p value, which is highlighted in bold type if the null hypothesis was rejected. Note that the criterion p value was 0.01, or lower if a Bonferroni correction was applied, as indicated in Column 4. Finally, column 6 refers to the relevant figure, if applicable.