Intrinsic properties of principal neurons and PV interneurons
| Property | Principal neurons (n = 30) | PV interneurons (n = 25) |
|---|---|---|
| RMP, mV | −62.8 ± 0.8 | −65.9 ± 0.8 |
| Input resistance, MΩ | 111 ± 8 | 104 ± 9 |
| Capacitance, pF | 21.4 ± 2.43 | 14.3 ± 1.97 |
| Sag, mV | −2.1 ± 0.3 | −0.2 ± 0.1 |
| Time to first AP, ms | 65 ± 7 | 24 ± 6 |
| AP threshold, mV | −37.3 ± 0.7 | −36.1 ± 0.9 |
| Current injection, pAa | 165 ± 17 | 251 ± 17 |
| AP amplitude, mV | 107.1 ± 2.0 | 76.7 ± 1.1 |
| AHP amplitude, mVb | 8.3 ± 1.0 | 31.1 ± 0.9 |
| Spike half-width, ms | 0.91 ± 0.03 | 0.49 ± 0.01 |
| Mean firing frequency, Hz | 10.3 ± 0.6 | 38.1 ± 2.6 |
RMP, Resting membrane potential; AP, action potential; AHP, afterhyperpolarization. All values are mean ± SEM. All values are measured at the current step above threshold.
↵a Current injection is the amplitude of the injected current evoking action potential firing.
↵b AHP amplitude is measured from threshold to maximal afterhyperpolarization.