MNs | |||
---|---|---|---|
Parameters/conditions | Pre-OX | OXA 300 nm | Washout |
Rin (MΩ) | 80.60 ± 46.02 (13) | 102.43 ± 38.41 (13)** | 92.16 ± 43.04 (11)ns |
AP amplitude (mV) | 72.48 ± 8.89 (13) | 68.59 ± 10.61 (13)ns | 69.08 ± 10.54 (12)ns |
AP threshold (mV) | −51.08 ± 8.90 (13) | −51.32 ± 8.87 (13)ns | −52.34 ± 9.90 (12)ns |
Rheobase (pA) | 478.6 ± 211.4 (13) | 396.7 ± 181.7 (13)* | 433.1 ± 233.3 (11)ns |
Average F/I slope (pA/Hz) | 0.0855 ± 0.0692 (13) | 0.0699 ± 0.0451 (13)* | 0.0705 ± 0.0284 (10)ns |
Instantaneous F/I slope (pA/Hz) | 0.1786 ± 0.206 (13) | 0.1468 ± 0.165 (13)ns | 0.1505 ± 0.209 (10)ns |
Values are the mean ± SD (number of motoneurons). Report of the statistical significance between control condition, pre-OX and OXA at 300 nm, and the control and washout of OXA for the following parameters: AP amplitude; action potential amplitude, AP threshold, action potential threshold, rheobase; average F/I slope, average frequency of spiking/intensity of current-injected slope; instantaneous F/I slope, instantaneous frequency/intensity slope. One-way repeated-measures ANOVA followed by Student–Newman–Keuls post hoc test was used to determine the significance between conditions.
nsp > 0.05; *p ≤ 0.05; **p ≤ 0.01.