Orexin A does not affect the intrinsic properties recorded from dCINs
| dCINs | |||
|---|---|---|---|
| Parameters/conditions | Pre-OX | OXA 300 nm | Washout |
| Rin (MΩ) | 629.8 ± 527.2 (10) | 626 ± 520.0 (10)ns | 462.6 ± 217.0 (8)ns |
| AP amplitude (mV) | 73.69 ± 10.33 (10) | 70.87 ± 9.25 (10)ns | 70.82 ± 8.11 (9)ns |
| AP threshold (mV) | −57.74 ± 4.19 (10) | −57.03 ± 3.2 (10)ns | −57.91 ± 2.86 (10)ns |
| Rheobase (pA) | 52.11 ± 25.07 (10) | 52.54 ± 31.09 (10)ns | 51.58 ± 27.71 (9)ns |
| Average F/I slope (pA/Hz) | 0.3348 ± 0.16 (10) | 0.2960 ± 0.181 (10)ns | 0.2965 ± 0.127 (7)ns |
| Instantaneous F/I slope (pA/Hz) | 0.3996 ± 0.335 (10) | 0.3896 ± 0.318 (10)ns | 0.3512 ± 0.098 (7)ns |
Values are the mean ± SD (number of dCINs). Report of the statistical significance between control condition pre-OX and OXA at 300 nm, and the control and washout of OXA. ANOVA followed by Student–Newman–Keuls post hoc test was used to determine the significance between conditions.
nsp > 0.05.