RT Journal Article SR Electronic T1 Development and Organization of the Evolutionarily Conserved Three-Layered Olfactory Cortex JF eneuro JO eNeuro FD Society for Neuroscience SP ENEURO.0193-16.2016 DO 10.1523/ENEURO.0193-16.2016 VO 4 IS 1 A1 Klingler, Esther YR 2017 UL http://www.eneuro.org/content/4/1/ENEURO.0193-16.2016.abstract AB The olfactory cortex is part of the mammalian cerebral cortex together with the neocortex and the hippocampus. It receives direct input from the olfactory bulbs and participates in odor discrimination, association, and learning (Bekkers and Suzuki, 2013). It is thought to be an evolutionarily conserved paleocortex, which shares common characteristics with the three-layered general cortex of reptiles (Aboitiz et al., 2002). The olfactory cortex has been studied as a “simple model” to address sensory processing, though little is known about its precise cell origin, diversity, and identity. While the development and the cellular diversity of the six-layered neocortex are increasingly understood, the olfactory cortex remains poorly documented in these aspects. Here is a review of current knowledge of the development and organization of the olfactory cortex, keeping the analogy with those of the neocortex. The comparison of olfactory cortex and neocortex will allow the opening of evolutionary perspectives on cortical development.