PT  - JOURNAL ARTICLE
AU  - Frédéric Crevecoeur
AU  - Jean-Louis Thonnard
AU  - Philippe Lefèvre
AU  - Stephen H. Scott
TI  - Long-Latency Feedback Coordinates Upper-Limb and Hand Muscles during Object Manipulation Tasks
AID  - 10.1523/ENEURO.0129-15.2016
DP  - 2016 Jan 01
TA  - eneuro
PG  - ENEURO.0129-15.2016
VI  - 3
IP  - 1
4099  - http://www.eneuro.org/content/3/1/ENEURO.0129-15.2016.short
4100  - http://www.eneuro.org/content/3/1/ENEURO.0129-15.2016.full
SO  - eneuro2016 Jan 01; 3
AB  - Suppose that someone bumps into your arm at a party while you are holding a glass of wine. Motion of the disturbed arm will engage rapid and goal-directed feedback responses in the upper-limb. Although such responses can rapidly counter the perturbation, it is also clearly desirable not to destabilize your grasp and/or spill the wine. Here we investigated how healthy humans maintain a stable grasp following perturbations by using a paradigm that requires spatial tuning of the motor response dependent on the location of a virtual target. Our results highlight a synchronized expression of target-directed feedback in shoulder and hand muscles occurring at ∼60 ms. Considering that conduction delays are longer for the more distal hand muscles, these results suggest that target-directed responses in hand muscles were initiated before those for the shoulder muscles. These results show that long-latency feedback can coordinate upper limb and hand muscles during object manipulation tasks.