PT - JOURNAL ARTICLE AU - Grandjean, Joanes AU - Lake, Evelyn M. R. AU - Pagani, Marco AU - Mandino, Francesca TI - What <em>N</em> Is N-ough for MRI-Based Animal Neuroimaging? AID - 10.1523/ENEURO.0531-23.2024 DP - 2024 Mar 01 TA - eneuro PG - ENEURO.0531-23.2024 VI - 11 IP - 3 4099 - http://www.eneuro.org/content/11/3/ENEURO.0531-23.2024.short 4100 - http://www.eneuro.org/content/11/3/ENEURO.0531-23.2024.full SO - eNeuro2024 Mar 01; 11 AB - Fueled by the recent and controversial brain-wide association studies in humans, the animal neuroimaging community has also begun questioning whether using larger sample sizes is necessary for ethical and effective scientific progress. In this opinion piece, we illustrate two opposing views on sample size extremes in MRI-based animal neuroimaging.