RT Journal Article
SR Electronic
T1 High-Gamma Activity Is Coupled to Low-Gamma Oscillations in Precentral Cortices and Modulates with Movement and Speech
JF eneuro
JO eNeuro
FD Society for Neuroscience
SP ENEURO.0163-23.2023
DO 10.1523/ENEURO.0163-23.2023
VO 11
IS 2
A1 Nie, Jeffrey Z.
A1 Flint, Robert D.
A1 Prakash, Prashanth
A1 Hsieh, Jason K.
A1 Mugler, Emily M.
A1 Tate, Matthew C.
A1 Rosenow, Joshua M.
A1 Slutzky, Marc W.
YR 2024
UL http://www.eneuro.org/content/11/2/ENEURO.0163-23.2023.abstract
AB Planning and executing motor behaviors requires coordinated neural activity among multiple cortical and subcortical regions of the brain. Phase–amplitude coupling between the high-gamma band amplitude and the phase of low frequency oscillations (theta, alpha, beta) has been proposed to reflect neural communication, as has synchronization of low-gamma oscillations. However, coupling between low-gamma and high-gamma bands has not been investigated. Here, we measured phase–amplitude coupling between low- and high-gamma in monkeys performing a reaching task and in humans either performing finger-flexion or word-reading tasks. We found significant coupling between low-gamma phase and high-gamma amplitude in multiple sensorimotor and premotor cortices of both species during all tasks. This coupling modulated with the onset of movement. These findings suggest that interactions between the low and high gamma bands are markers of network dynamics related to movement and speech generation.