RT Journal Article
SR Electronic
T1 Phase Property of Envelope-Tracking EEG Response Is Preserved in Patients with Disorders of Consciousness
JF eneuro
JO eNeuro
FD Society for Neuroscience
SP ENEURO.0130-23.2023
DO 10.1523/ENEURO.0130-23.2023
VO 10
IS 8
A1 Jia, Ziting
A1 Xu, Chuan
A1 Li, Jingqi
A1 Gao, Jian
A1 Ding, Nai
A1 Luo, Benyan
A1 Zou, Jiajie
YR 2023
UL http://www.eneuro.org/content/10/8/ENEURO.0130-23.2023.abstract
AB When listening to speech, the low-frequency cortical response below 10 Hz can track the speech envelope. Previous studies have demonstrated that the phase lag between speech envelope and cortical response can reflect the mechanism by which the envelope-tracking response is generated. Here, we analyze whether the mechanism to generate the envelope-tracking response is modulated by the level of consciousness, by studying how the stimulus-response phase lag is modulated by the disorder of consciousness (DoC). It is observed that DoC patients in general show less reliable neural tracking of speech. Nevertheless, the stimulus-response phase lag changes linearly with frequency between 3.5 and 8 Hz, for DoC patients who show reliable cortical tracking to speech, regardless of the consciousness state. The mean phase lag is also consistent across these DoC patients. These results suggest that the envelope-tracking response to speech can be generated by an automatic process that is barely modulated by the consciousness state.