RT Journal Article SR Electronic T1 Visual Neuroscience Methods for Marmosets: Efficient Receptive Field Mapping and Head-Free Eye Tracking JF eneuro JO eNeuro FD Society for Neuroscience SP ENEURO.0489-20.2021 DO 10.1523/ENEURO.0489-20.2021 VO 8 IS 3 A1 Patrick Jendritza A1 Frederike J. Klein A1 Gustavo Rohenkohl A1 Pascal Fries YR 2021 UL http://www.eneuro.org/content/8/3/ENEURO.0489-20.2021.abstract AB The marmoset has emerged as a promising primate model system, in particular for visual neuroscience. Many common experimental paradigms rely on head fixation and an extended period of eye fixation during the presentation of salient visual stimuli. Both of these behavioral requirements can be challenging for marmosets. Here, we present two methodological developments, each addressing one of these difficulties. First, we show that it is possible to use a standard eye-tracking system without head fixation to assess visual behavior in the marmoset. Eye-tracking quality from head-free animals is sufficient to obtain precise psychometric functions from a visual acuity task. Second, we introduce a novel method for efficient receptive field (RF) mapping that does not rely on moving stimuli but uses fast flashing annuli and wedges. We present data recorded during head-fixation in areas V1 and V6 and show that RF locations are readily obtained within a short period of recording time. Thus, the methodological advancements presented in this work will contribute to establish the marmoset as a valuable model in neuroscience.