PT  - JOURNAL ARTICLE
AU  - K.G. Garner
AU  - M.I. Garrido
AU  - P.E. Dux
TI  - Cognitive Capacity Limits Are Remediated by Practice-Induced Plasticity between the Putamen and Pre-Supplementary Motor Area
AID  - 10.1523/ENEURO.0139-20.2020
DP  - 2020 Jul 01
TA  - eneuro
PG  - ENEURO.0139-20.2020
VI  - 7
IP  - 4
4099  - http://www.eneuro.org/content/7/4/ENEURO.0139-20.2020.short
4100  - http://www.eneuro.org/content/7/4/ENEURO.0139-20.2020.full
SO  - eNeuro2020 Jul 01; 7
AB  - Humans show striking limitations in information processing when multitasking yet can modify these limits with practice. Such limitations have been linked to a frontal-parietal network, but recent models of decision-making implicate a striatal-cortical network. We adjudicated these accounts by investigating the circuitry underpinning multitasking in 100 human individuals and the plasticity caused by practice. We observed that multitasking costs, and their practice-induced remediation, are best explained by modulations in information transfer between the striatum and the cortical areas that represent stimulus-response mappings. Specifically, our results support the view that multitasking stems at least in part from taxation in information sharing between the putamen and pre-supplementary motor area (pre-SMA). Moreover, we propose that modulations to information transfer between these two regions leads to practice-induced improvements in multitasking.