Beyond motor noise: considering other causes of impaired reinforcement learning in cerebellar patients

Abstract

Significance statement Motor and reinforcement learning have been classically linked to functionally independent brain networks centered on the cerebellum and the basal ganglia respectively. In a recent study published in eNeuro, Therrien et al. (2018) showed that increasing motor noise in healthy subjects disrupts reinforcement learning. However, this impairment remained well below that detected in cerebellar patients even when motor noise in healthy subjects was adjusted to match that observed in the patients. This suggests that impaired reinforcement learning following cerebellar damage cannot be solely accounted for by altered motor noise in these patients. Based on recent anatomical and functional evidence, we argue that the cerebellum may directly contribute to reinforcement learning, consistent with its tight connections with the basal ganglia.