Article Figures & Data
Figures
- Figure 1.
Clusters showing significant differences between deprived Romanian adoptees and nondeprived United Kingdom adoptees in the log-transformed Jacobian determinant of local white matter deformations. Statistical clusters that were smaller in volume in the deprived group (compared with the nondeprived group) are shown in blue, while regions that were bigger are shown in red. Statistical maps are shown as an overlay on a white matter map of the general population with whiter areas indicating higher FA. The FA map was also used as a binarized mask (threshold FA ≥ 0.20) for statistical analysis to assure that only white matter was included. The first two rows show axial slices. The last row shows a sagittal view, a coronal view and a 3D rendering. L, left; R, right; A, anterior; P, posterior; FA, fractional anisotropy. The figure was created using the software MRIcroGL (https://www.nitrc.org/projects/mricrogl/) and ParaView (https://www.paraview.org/).
Tables
- Table 1
Clusters showing significant differences between deprived Romanian adoptees and nondeprived United Kingdom adoptees in local white matter volumes (all pFWE < 0.05)
Cluster index Cluster size (mm3) Hemi-sphere T value Max voxel MNI
coordinates (mm)Annotation x y z Nondeprived > deprived 1 12,460 L 6.43 −12 −23 −29 Brain stem 6.28 −33 −17 −5 IFOF 5.91 −33 −24 1 IFOF 5.88 −33 −25 −1 IFOF 5.48 −23 −17 −6 ILF 2 4760 R 4.58 33 −22 1 IFOF 4.53 33 −22 −1 IFOF 4.43 26 −33 9 IFOF 4.28 29 −26 1 ILF 3 1791 L 4.56 −7 −47 17 Cingulum 4.49 −12 −41 28 Cingulum 4 398 L 4.14 −34 −70 6 ILF 5 280 L 4.21 −9 −82 21 ILF 6 217 L 4.1 −41 −23 −13 ILF 7 140 L 4.78 −11 −67 47 ILF 8 117 L 3.8 −12 −57 51 Cingulum 9 98 L 3.37 −39 −37 33 SLF 10 97 L 3.86 −43 −35 −7 ILF 11 59 L 3.86 −31 −60 13 ILF 12 7 L 3.49 −37 −27 −16 ILF Deprived > nondeprived 1 82 L 6.00 −32 −4 −16 Uncinate Deprivation duration No significant clusters Subnutrition No significant clusters L, left; R, right; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus. Threshold-free cluster enhancement (TFCE) was applied and all analyses were controlled for family-wise error rate (FWE).
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