Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT

User menu

Search

  • Advanced search
eNeuro

eNeuro

Advanced Search

 

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Blog
    • Collections
    • Podcast
  • TOPICS
    • Cognition and Behavior
    • Development
    • Disorders of the Nervous System
    • History, Teaching and Public Awareness
    • Integrative Systems
    • Neuronal Excitability
    • Novel Tools and Methods
    • Sensory and Motor Systems
  • ALERTS
  • FOR AUTHORS
  • ABOUT
    • Overview
    • Editorial Board
    • For the Media
    • Privacy Policy
    • Contact Us
    • Feedback
  • SUBMIT
PreviousNext
Research ArticleResearch Article: New Research, Sensory and Motor Systems

De Novo Brain-Computer Interfacing Deforms Manifold of Populational Neural Activity Patterns in Human Cerebral Cortex

Seitaro Iwama, Yichi Zhang and Junichi Ushiba
eNeuro 14 November 2022, 9 (6) ENEURO.0145-22.2022; DOI: https://doi.org/10.1523/ENEURO.0145-22.2022
Seitaro Iwama
1School of Fundamental Science and Technology, Graduate School of Keio University, Kanagawa, 223-8522, Japan
2Japan Society for the Promotion of Science, Tokyo, 102-0083, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Seitaro Iwama
Yichi Zhang
1School of Fundamental Science and Technology, Graduate School of Keio University, Kanagawa, 223-8522, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Junichi Ushiba
3Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Kanagawa, 223-8522, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/ENEURO.0145-22.2022
PubMed 
36376067
Published By 
Society for Neuroscience
History 
  • Received April 4, 2022
  • Revision received October 27, 2022
  • Accepted November 2, 2022
  • Published online November 14, 2022.
Copyright & Usage 
Copyright © 2022 Iwama et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Seitaro Iwama1,2,
  2. Yichi Zhang1 and
  3. Junichi Ushiba3
  1. 1School of Fundamental Science and Technology, Graduate School of Keio University, Kanagawa, 223-8522, Japan
  2. 2Japan Society for the Promotion of Science, Tokyo, 102-0083, Japan
  3. 3Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Kanagawa, 223-8522, Japan
  1. Correspondence should be addressed to Junichi Ushiba at ushiba{at}bio.keio.ac.jp.
View Full Text

Author contributions

  1. Author contributions: S.I., Y.Z., and J.U. designed research; S.I. and Y.Z. performed research; S.I. and Y.Z. contributed unpublished reagents/analytic tools; S.I. and Y.Z. analyzed data; S.I., Y.Z., and J.U. wrote the paper.

Disclosures

  • J.U. is a founder and representative director of the university startup company, LIFESCAPES Inc., involved in the research, development, and sales of rehabilitation devices including brain-computer interfaces, he receives a salary from LIFESCAPES Inc., and holds shares in LIFESCAPES Inc. This company does not have any relationships with the device or setup used in the current study. All other authors declare no competing financial interests.

  • This work was supported by the Keio Institute of Pure and Applied Sciences (KiPAS) Research Program, the Japan Society for the Promotion of Science KAKENHI Grant Number 20H05923 (to J.U.), and the Japan Science and Technology Agency, CREST Grant Number JPMJCR17A3 (to J.U.), including the AIP Challenge Program, Japan.

Funding

  • Keio Institute for Pure and Applied Sciences (KiPAS) research program

  • MEXT | Japan Society for the Promotion of Science (JSPS)

    20H05923
  • MEXT | Japan Science and Technology Agency (JST)

    JPMJCR17A3

Other Version

  • You are viewing the most recent version of this article.
  • previous version (November 14, 2022).

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2023-03-23
to
E.g., 2023-03-23

Article usage: November 2022 to March 2023

AbstractFullPdf
Nov 202233467105
Dec 20225324479
Total 2022387311184
Jan 2023246729
Feb 202316569
Mar 2023104711
Total 20235017049
Total437481233
Back to top

In this issue

eneuro: 9 (6)
eNeuro
Vol. 9, Issue 6
November/December 2022
  • Table of Contents
  • Index by author
  • Ed Board (PDF)
Email

Thank you for sharing this eNeuro article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
De Novo Brain-Computer Interfacing Deforms Manifold of Populational Neural Activity Patterns in Human Cerebral Cortex
(Your Name) has forwarded a page to you from eNeuro
(Your Name) thought you would be interested in this article in eNeuro.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
De Novo Brain-Computer Interfacing Deforms Manifold of Populational Neural Activity Patterns in Human Cerebral Cortex
Seitaro Iwama, Yichi Zhang, Junichi Ushiba
eNeuro 14 November 2022, 9 (6) ENEURO.0145-22.2022; DOI: 10.1523/ENEURO.0145-22.2022

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
De Novo Brain-Computer Interfacing Deforms Manifold of Populational Neural Activity Patterns in Human Cerebral Cortex
Seitaro Iwama, Yichi Zhang, Junichi Ushiba
eNeuro 14 November 2022, 9 (6) ENEURO.0145-22.2022; DOI: 10.1523/ENEURO.0145-22.2022
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Significance Statement
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Footnotes
    • References
    • Synthesis
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • brain-computer interface
  • de novo learning
  • neural plasticity
  • nonlinear dimensionality reduction
  • sensorimotor activity

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Research Article: New Research

  • Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins
  • The Mobility of Neurofilaments in Mature Myelinated Axons of Adult Mice
  • A Conserved Role for Stomatin Domain Genes in Olfactory Behavior
Show more Research Article: New Research

Sensory and Motor Systems

  • Different control strategies drive interlimb differences in performance and adaptation during reaching movements in novel dynamics
  • The nasal solitary chemosensory cell signaling pathway triggers mouse avoidance behavior to inhaled nebulized irritants
  • Taste-odor association learning alters the dynamics of intra-oral odor responses in the posterior piriform cortex of awake rats
Show more Sensory and Motor Systems

Subjects

  • Sensory and Motor Systems

  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Latest Articles
  • Issue Archive
  • Blog
  • Browse by Topic

Information

  • For Authors
  • For the Media

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
  • Feedback
(eNeuro logo)
(SfN logo)

Copyright © 2023 by the Society for Neuroscience.
eNeuro eISSN: 2373-2822

The ideas and opinions expressed in eNeuro do not necessarily reflect those of SfN or the eNeuro Editorial Board. Publication of an advertisement or other product mention in eNeuro should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in eNeuro.