Article Information
- Received April 7, 2021
- Revision received July 20, 2022
- Accepted August 23, 2022
- Published online September 8, 2022.
Author Information
- P. J. Nicholls1,
- Thomas F. Pack2,3,
- Nikhil M. Urs2,
- Sunil Kumar1,
- Yang Zhou2,
- Gabriel Ichim10,
- Joshua D. Ginzel2,
- Gabor Turu2,
- Evan Calabrese4,5,
- Wendy L. Roberts2,
- Ping Fan6,
- Valeriy G. Ostapchenko11,
- Monica S. Guzman Lenis11,12,
- Flavio Beraldo11,13,
- Jiri Hatina14,
- Vania F. Prado11,12,13,
- Marco A. M. Prado11,12,13,
- Ivan Spasojevic6,
- Joshua C. Snyder2,9,
- Kafui Dzirasa1,4,7,
- G. Allan Johnson4,5,8 and
- Marc G. Caron2,6,7,†
- 1Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710
- 2Department of Cell Biology, Duke University Medical Center, Durham, NC 27710
- 3Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710
- 4Department of Biomedical Engineering, Duke University Medical Center, Durham, NC 27710
- 5Center for In Vivo Microscopy, Department of Radiology, Duke University Medical Center, Durham, NC 27710
- 6Department of Medicine, Duke University Medical Center, Durham, NC 27710
- 7Department of Neurobiology, Duke University Medical Center, Durham, NC 27710
- 8Department of Physics, Duke University, Durham, NC 27710
- 9Department of Surgery, Duke University Medical Center, Durham, NC 27710
- 10Center for Research on Cancer in Lyon, University of Lyon, Lyon 69008, France
- 11Robarts Research Institute, University of Western Ontario, London, Ontario N6A 3K7, Canada
- 12Department of Anatomy and Cell Biology, University of Western Ontario, London, Ontario N6A 3K7, Canada
- 13Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario N6A 3K7, Canada
- 14Institute of Biology, Charles University, Plzen CZ-32300, Czech Republic
- Correspondence should be addressed to P. J. Nicholls at peter.nicholls{at}duke.edu.
Author contributions
Author contributions: P.J.N., T.F.P., N.M.U., S.K., Y.Z., G.I., J.D.G., G.T., E.C., W.L.R., P.F., V.G.O., M.S.G.L., F.B., J.H., V.F.P., M.A.M.P., I.S., J.C.S., K.D., G.A.J., and M.G.C. designed research; P.J.N., T.F.P., N.M.U., S.K., Y.Z., G.I., J.D.G., G.T., E.C., W.L.R., P.F., V.G.O., M.S.G.L., F.B., J.H., I.S., and K.D. performed research; P.J.N., T.F.P., N.M.U., J.D.G., and E.C. contributed unpublished reagents/analytic tools; P.J.N., T.F.P., S.K., G.I., P.F., V.F.P., M.A.M.P., I.S., J.C.S., K.D., G.A.J., and M.G.C. analyzed data; P.J.N. wrote the paper.
Disclosures
The authors declare no competing financial interests.
This work was supported by National Institutes of Health Grants 1R21NS081513 (to P.J.N.), 8P41EB015897 (to G.A.J.), and 2R01MH079201 and 5R37MH073853 (to M.G.C.) and by Canadian Institutes of Health Research Grants MOP 93651, 12600, and 89919 (to M.A.M.P.). Support from the Pall Family Foundation and Lennon Family Foundation to MGC is greatly appreciated. Ki determinations were provided by the National Institute of Mental Health’s Psychoactive Drug Screening Program, Contract #HHSN-271-2013-00017-C.
↵†Deceased, Apr. 25, 2022.
Funding
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)
1R21NS081513HHS | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB)
8P41EB015897HHS | NIH | National Institute of Mental Health (NIMH)
2R01MH079201; 5R37MH073853Canadian Institutes of Health Research
MOP 93651; MOP 12600; MOP 89919Pall Family Foundation
N/ALennon Family Foundation
N/A
Other Version
- You are viewing the most recent version of this article.
- previous version (September 08, 2022).
Article usage
In this issue
