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Research ArticleResearch Article: New Research, Cognition and Behavior

Sources of Variation in the Spectral Slope of the Sleep EEG

Nataliia Kozhemiako, Dimitris Mylonas, Jen Q. Pan, Michael J. Prerau, Susan Redline and Shaun M. Purcell
eNeuro 19 September 2022, 9 (5) ENEURO.0094-22.2022; DOI: https://doi.org/10.1523/ENEURO.0094-22.2022
Nataliia Kozhemiako
1Department of Psychiatry, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA 02115
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  • ORCID record for Nataliia Kozhemiako
Dimitris Mylonas
2Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114
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Jen Q. Pan
3Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA 02142
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Michael J. Prerau
1Department of Psychiatry, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA 02115
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Susan Redline
4Department of Medicine, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA 02115
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Shaun M. Purcell
1Department of Psychiatry, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA 02115
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0094-22.2022
PubMed 
36123117
Published By 
Society for Neuroscience
History 
  • Received March 4, 2022
  • Revision received July 1, 2022
  • Accepted July 30, 2022
  • Published online September 19, 2022.
Copyright & Usage 
Copyright © 2022 Kozhemiako et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Nataliia Kozhemiako1,
  2. Dimitris Mylonas2,
  3. Jen Q. Pan3,
  4. Michael J. Prerau1,
  5. Susan Redline4 and
  6. Shaun M. Purcell1
  1. 1Department of Psychiatry, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA 02115
  2. 2Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114
  3. 3Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA 02142
  4. 4Department of Medicine, Brigham & Women’s Hospital, Harvard Medical School, Boston, MA 02115
  1. Correspondence should be addressed to Shaun M. Purcell at smpurcell{at}bwh.harvard.edu.
View Full Text

Author contributions

  1. Author contributions: J.Q.P., M.J.P., S.R., and S.M.P. designed research; N.K. and S.M.P. performed research; S.M.P. contributed unpublished reagents/analytic tools; N.K. and S.M.P. analyzed data; N.K., D.M., J.Q.P., S.R., and S.M.P. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by the National Institutes of Health (NIH)/National Institute of Mental Health (NIMH) Grant R03 MH108908 (to S.M.P.), NIH/National Heart, Lung, and Blood Institute (NHLBI) Grants R01 HL146339 and R21 HL145492 (to S.M.P.), and the NIH/National Institute on Minority Health and Health Disparities (NIMHD) Grant R21 MD012738 (to S.M.P.).

  • Acknowledgements: We thank the National Sleep Research Resource (NSRR) staff and all investigators contributing data to the NSRR. This study has been published as a preprint at bioRxiv (doi.org/10.1101/2021.11.08.467763).

Funding

  • HHS | NIH | National Institute of Mental Health (NIMH)

    R03 MH108908
  • HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI)

    R01 HL146339; R21 HL145492
  • HHS | NIH | National Institute on Minority Health and Health Disparities (NIMHD)

    R21 MD012738

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Sources of Variation in the Spectral Slope of the Sleep EEG
Nataliia Kozhemiako, Dimitris Mylonas, Jen Q. Pan, Michael J. Prerau, Susan Redline, Shaun M. Purcell
eNeuro 19 September 2022, 9 (5) ENEURO.0094-22.2022; DOI: 10.1523/ENEURO.0094-22.2022

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Sources of Variation in the Spectral Slope of the Sleep EEG
Nataliia Kozhemiako, Dimitris Mylonas, Jen Q. Pan, Michael J. Prerau, Susan Redline, Shaun M. Purcell
eNeuro 19 September 2022, 9 (5) ENEURO.0094-22.2022; DOI: 10.1523/ENEURO.0094-22.2022
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Keywords

  • 1/f slope
  • developmental changes
  • electroencephalography
  • individual variability
  • spectral slope

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