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Research ArticleResearch Article: New Research, Sensory and Motor Systems

Behavioral Forgetting of Olfactory Learning Is Mediated by Interneuron-Regulated Network Plasticity in Caenorhabditis elegans

Jamine Hooi-Min Teo, Itsuki Kurokawa, Yuuki Onishi, Noriko Sato, Tomohiro Kitazono, Terumasa Tokunaga, Manabi Fujiwara and Takeshi Ishihara
eNeuro 17 August 2022, 9 (4) ENEURO.0084-22.2022; https://doi.org/10.1523/ENEURO.0084-22.2022
Jamine Hooi-Min Teo
1Graduate School of System Life Science, Kyushu University, Fukuoka 819-0395, Japan
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Itsuki Kurokawa
1Graduate School of System Life Science, Kyushu University, Fukuoka 819-0395, Japan
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Yuuki Onishi
1Graduate School of System Life Science, Kyushu University, Fukuoka 819-0395, Japan
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Noriko Sato
2Department of Artificial Intelligence, Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka 820-8502, Japan
3Department of Biology, Faculty of Science, Kyushu University, Fukuoka 819-0395, Japan
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Tomohiro Kitazono
1Graduate School of System Life Science, Kyushu University, Fukuoka 819-0395, Japan
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Terumasa Tokunaga
2Department of Artificial Intelligence, Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka 820-8502, Japan
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Manabi Fujiwara
1Graduate School of System Life Science, Kyushu University, Fukuoka 819-0395, Japan
3Department of Biology, Faculty of Science, Kyushu University, Fukuoka 819-0395, Japan
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Takeshi Ishihara
1Graduate School of System Life Science, Kyushu University, Fukuoka 819-0395, Japan
3Department of Biology, Faculty of Science, Kyushu University, Fukuoka 819-0395, Japan
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0084-22.2022
PubMed 
35977825
Published By 
Society for Neuroscience
History 
  • Received February 23, 2022
  • Revision received August 5, 2022
  • Accepted August 9, 2022
  • Published online August 17, 2022.
Copyright & Usage 
Copyright © 2022 Teo et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Jamine Hooi-Min Teo1,
  2. Itsuki Kurokawa1,
  3. Yuuki Onishi1,
  4. Noriko Sato2,3,
  5. Tomohiro Kitazono1,
  6. Terumasa Tokunaga2,
  7. Manabi Fujiwara1,3 and
  8. Takeshi Ishihara1,3
  1. 1Graduate School of System Life Science, Kyushu University, Fukuoka 819-0395, Japan
  2. 2Department of Artificial Intelligence, Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka 820-8502, Japan
  3. 3Department of Biology, Faculty of Science, Kyushu University, Fukuoka 819-0395, Japan
  1. Correspondence should be addressed to Takeshi Ishihara at ishihara.takeshi.718{at}m.kyushu-u.ac.jp.
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Author contributions

  1. Author contributions: J.H.-M.T., T.K., T.T., M.F., and T.I. designed research; J.H.-M.T., I.K., Y.O., and N.S. performed research; J.H.-M.T. analyzed data; J.H.-M.T. and T.I. wrote the paper.

Disclosures

  • The authors declare no competing financial interests

  • This work was supported by Japan Society for the Promotion of Science KAKENHI Grants J19H03326, J18H05135, J17H06113, J16H06545, and 25115009 (to T.I.); and by NTT-Kyushu University Collaborative Research, and PRESTO Grants JPMJPR1875 and 7700000461. J.H.-M.T. is supported by a Japanese Government Scholarship (MEXT).

Funding

  • MEXT | Japan Society for the Promotion of Science (JSPS)

    J19H03326; J18H05135; J17H06113; J16H06545; and 25115009
  • MEXT | JST | Precursory Research for Embryonic Science and Technology (PRESTO)

    JPMJPR1875

Other Version

  • You are viewing the most recent version of this article.
  • previous version (August 17, 2022).

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Behavioral Forgetting of Olfactory Learning Is Mediated by Interneuron-Regulated Network Plasticity in Caenorhabditis elegans
Jamine Hooi-Min Teo, Itsuki Kurokawa, Yuuki Onishi, Noriko Sato, Tomohiro Kitazono, Terumasa Tokunaga, Manabi Fujiwara, Takeshi Ishihara
eNeuro 17 August 2022, 9 (4) ENEURO.0084-22.2022; DOI: 10.1523/ENEURO.0084-22.2022

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Behavioral Forgetting of Olfactory Learning Is Mediated by Interneuron-Regulated Network Plasticity in Caenorhabditis elegans
Jamine Hooi-Min Teo, Itsuki Kurokawa, Yuuki Onishi, Noriko Sato, Tomohiro Kitazono, Terumasa Tokunaga, Manabi Fujiwara, Takeshi Ishihara
eNeuro 17 August 2022, 9 (4) ENEURO.0084-22.2022; DOI: 10.1523/ENEURO.0084-22.2022
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Keywords

  • C. elegans
  • circuit plasticity
  • forgetting
  • memory
  • olfactory learning

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