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Research ArticleResearch Article: Negative Results, Disorders of the Nervous System

14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer’s Disease Mouse Models

Mary Gannon, Bing Wang, Sara Anne Stringfellow, Stephan Quintin, Itzel Mendoza, Thanushri Srikantha, A. Claire Roberts, Takashi Saito, Takaomi C. Saido, Erik D. Roberson and Talene A. Yacoubian
eNeuro 13 June 2022, 9 (3) ENEURO.0368-21.2022; https://doi.org/10.1523/ENEURO.0368-21.2022
Mary Gannon
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
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Bing Wang
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
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Sara Anne Stringfellow
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
2University of South Alabama College of Medicine, Mobile, AL 36688
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Stephan Quintin
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
3Medical Scientist Training Program, University of Florida, Gainesville, FL 32611
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Itzel Mendoza
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
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Thanushri Srikantha
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
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A. Claire Roberts
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
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Takashi Saito
4RIKEN Center for Brain Science, Saitama 351-0198, Japan
5Department of Neurocognitive Science, Institute of Brain Science, Nagoya City University Graduates School of Medical Sciences, Nagaya 467-8601, Japan
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Takaomi C. Saido
4RIKEN Center for Brain Science, Saitama 351-0198, Japan
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Erik D. Roberson
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
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Talene A. Yacoubian
1Center for Neurodegeneration and Experimental Therapeutics, Department of Neurology, University of Alabama at Birmingham, Birmingham, AL 35294
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eneuro: 9 (3)
eNeuro
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May/June 16
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14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer’s Disease Mouse Models
Mary Gannon, Bing Wang, Sara Anne Stringfellow, Stephan Quintin, Itzel Mendoza, Thanushri Srikantha, A. Claire Roberts, Takashi Saito, Takaomi C. Saido, Erik D. Roberson, Talene A. Yacoubian
eNeuro 13 June 2022, 9 (3) ENEURO.0368-21.2022; DOI: 10.1523/ENEURO.0368-21.2022

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14-3-3θ Does Not Protect against Behavioral or Pathological Deficits in Alzheimer’s Disease Mouse Models
Mary Gannon, Bing Wang, Sara Anne Stringfellow, Stephan Quintin, Itzel Mendoza, Thanushri Srikantha, A. Claire Roberts, Takashi Saito, Takaomi C. Saido, Erik D. Roberson, Talene A. Yacoubian
eNeuro 13 June 2022, 9 (3) ENEURO.0368-21.2022; DOI: 10.1523/ENEURO.0368-21.2022
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Keywords

  • β-amyloid
  • 14-3-3
  • Alzheimer’s disease
  • Cortex
  • hippocampus
  • mouse model

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Research Article: Negative Results

  • Expression of HDAC3-Y298H Point Mutant in Medial Habenula Cholinergic Neurons Has No Effect on Cocaine-Induced Behaviors
  • Alpha-Synuclein Phosphomimetic Y39E and S129D Knock-In Mice Show Cytosolic Alpha-Synuclein Localization without Developing Neurodegeneration or Motor Deficits
  • Paired Stimulation of Different Digits for 30 min Does Not Produce Long-Term Plastic Changes in the Human Cutaneomuscular Reflex
Show more Research Article: Negative Results

Disorders of the Nervous System

  • Expression of HDAC3-Y298H Point Mutant in Medial Habenula Cholinergic Neurons Has No Effect on Cocaine-Induced Behaviors
  • Alpha-Synuclein Phosphomimetic Y39E and S129D Knock-In Mice Show Cytosolic Alpha-Synuclein Localization without Developing Neurodegeneration or Motor Deficits
  • Paired Stimulation of Different Digits for 30 min Does Not Produce Long-Term Plastic Changes in the Human Cutaneomuscular Reflex
Show more Disorders of the Nervous System

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