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Research ArticleResearch Article: New Research, Development

Conditions for Synaptic Specificity during the Maintenance Phase of Synaptic Plasticity

Marco A. Huertas, Adam J. H. Newton, Robert A. McDougal, Todd Charlton Sacktor and Harel Z. Shouval
eNeuro 20 April 2022, 9 (3) ENEURO.0064-22.2022; DOI: https://doi.org/10.1523/ENEURO.0064-22.2022
Marco A. Huertas
1Department of Neurobiology and Anatomy, University of Texas Medical School, Houston, TX 77030
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Adam J. H. Newton
2Yale Center for Medical Informatics, New Haven, CT 06520
3Department of Biostatistics, Yale School of Public Health, New Haven, CT 06520
4Department of Physiology and Pharmacology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203
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Robert A. McDougal
2Yale Center for Medical Informatics, New Haven, CT 06520
3Department of Biostatistics, Yale School of Public Health, New Haven, CT 06520
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  • ORCID record for Robert A. McDougal
Todd Charlton Sacktor
5Department of Physiology, Pharmacology, Anesthesiology, and Neurology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203
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Harel Z. Shouval
1Department of Neurobiology and Anatomy, University of Texas Medical School, Houston, TX 77030
6Department Electrical and Computer Engineering, Rice University, Houston, TX 77005
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0064-22.2022
PubMed 
35443991
Published By 
Society for Neuroscience
History 
  • Received February 8, 2022
  • Accepted March 31, 2022
  • Published online April 20, 2022.
Copyright & Usage 
Copyright © 2022 Huertas et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Marco A. Huertas1,
  2. Adam J. H. Newton2,3,4,
  3. Robert A. McDougal2,3,
  4. Todd Charlton Sacktor5 and
  5. Harel Z. Shouval1,6
  1. 1Department of Neurobiology and Anatomy, University of Texas Medical School, Houston, TX 77030
  2. 2Yale Center for Medical Informatics, New Haven, CT 06520
  3. 3Department of Biostatistics, Yale School of Public Health, New Haven, CT 06520
  4. 4Department of Physiology and Pharmacology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203
  5. 5Department of Physiology, Pharmacology, Anesthesiology, and Neurology, SUNY Downstate Health Sciences University, Brooklyn, NY 11203
  6. 6Department Electrical and Computer Engineering, Rice University, Houston, TX 77005
  1. Correspondence should be addressed to Harel Z. Shouval at harel.shouval{at}uth.tmc.edu.
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Author contributions

  1. Author contributions: H.Z.S., M.A.H., and T.C.S. designed research; H.Z.S., M.A.H., A.J.H.N., and R.A.M. performed research; H.Z.S., M.A.H., and T.C.S. wrote the paper.

Disclosures

  • The authors declare no competing financial interests.

  • This work is supported by National Institutes of Health Grants RO1 DA034979 (to H.Z.S. and T.C.S.), RO1 MH53576 (to T.C.S.), 2R37 MH057068 (to T.C.S.), R01 MH086638 (to A.J.H.N. and R.A.M.), R01 NS105472 (to T.C.S), R01 NS108190 (to T.C.S), and MH115304 (to T.C.S).

Funding

  • NIH/NIDA

    R01 DA034970
  • NIH/NIMH

    RO1 MH53576; 2R37 MH057068

Other Version

  • previous version (April 20, 2022).
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eneuro: 9 (3)
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Conditions for Synaptic Specificity during the Maintenance Phase of Synaptic Plasticity
Marco A. Huertas, Adam J. H. Newton, Robert A. McDougal, Todd Charlton Sacktor, Harel Z. Shouval
eNeuro 20 April 2022, 9 (3) ENEURO.0064-22.2022; DOI: 10.1523/ENEURO.0064-22.2022

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Conditions for Synaptic Specificity during the Maintenance Phase of Synaptic Plasticity
Marco A. Huertas, Adam J. H. Newton, Robert A. McDougal, Todd Charlton Sacktor, Harel Z. Shouval
eNeuro 20 April 2022, 9 (3) ENEURO.0064-22.2022; DOI: 10.1523/ENEURO.0064-22.2022
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Keywords

  • LTP
  • maintenance
  • protein synthesis
  • synapse specificity
  • synaptic plasticity

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