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Research ArticleResearch Article: New Research, Cognition and Behavior

Partial Ablation of Postsynaptic Dopamine D2 Receptors in the Central Nucleus of the Amygdala Increases Risk Avoidance in Exploratory Tasks

Eric Casey, María Elena Avale, Alexxai Kravitz and Marcelo Rubinstein
eNeuro 24 February 2022, 9 (2) ENEURO.0528-21.2022; https://doi.org/10.1523/ENEURO.0528-21.2022
Eric Casey
1Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina
4Department of Psychiatry, Washington University St. Louis, St. Louis, MO 63108
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María Elena Avale
1Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina
2Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires 1428, Argentina
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Alexxai Kravitz
3Department of Anesthesiology, Washington University St. Louis, St. Louis, MO 63108
4Department of Psychiatry, Washington University St. Louis, St. Louis, MO 63108
5Department of Neuroscience and Biomedical Engineering, Washington University St. Louis, St. Louis, MO 63108
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Marcelo Rubinstein
1Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina
2Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires 1428, Argentina
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0528-21.2022
PubMed 
35210287
Published By 
Society for Neuroscience
History 
  • Received December 22, 2021
  • Revision received January 15, 2022
  • Accepted February 4, 2022
  • Published online February 24, 2022.
Copyright & Usage 
Copyright © 2022 Casey et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Eric Casey1,4,
  2. María Elena Avale1,2,
  3. Alexxai Kravitz3,4,5 and
  4. Marcelo Rubinstein1,2
  1. 1Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires 1428, Argentina
  2. 2Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires 1428, Argentina
  3. 3Department of Anesthesiology, Washington University St. Louis, St. Louis, MO 63108
  4. 4Department of Psychiatry, Washington University St. Louis, St. Louis, MO 63108
  5. 5Department of Neuroscience and Biomedical Engineering, Washington University St. Louis, St. Louis, MO 63108
  1. Correspondence should be addressed to Marcelo Rubinstein at mrubins{at}dna.uba.ar.
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Author contributions

  1. Author contributions: M.R., M.E.A., A.K., and E.C. designed research; M.E.A. and E.C. performed research; M.R. and E.C. analyzed data; M.R. and E.C. wrote the paper.

View Abstract

Disclosures

  • The authors declare no competing financial interests.

  • This work was supported by grants from the Agencia Nacional de Promoción Científica y Tecnológica, Argentina (M.R.) and a doctoral fellowship from Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina (E.C.).

Funding

  • Agencia Nacional de Promoción Científica y Tecnológica

    PICT-2018-01358

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  • You are viewing the most recent version of this article.
  • previous version (February 24, 2022).

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Partial Ablation of Postsynaptic Dopamine D2 Receptors in the Central Nucleus of the Amygdala Increases Risk Avoidance in Exploratory Tasks
Eric Casey, María Elena Avale, Alexxai Kravitz, Marcelo Rubinstein
eNeuro 24 February 2022, 9 (2) ENEURO.0528-21.2022; DOI: 10.1523/ENEURO.0528-21.2022

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Partial Ablation of Postsynaptic Dopamine D2 Receptors in the Central Nucleus of the Amygdala Increases Risk Avoidance in Exploratory Tasks
Eric Casey, María Elena Avale, Alexxai Kravitz, Marcelo Rubinstein
eNeuro 24 February 2022, 9 (2) ENEURO.0528-21.2022; DOI: 10.1523/ENEURO.0528-21.2022
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