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History
- Received November 16, 2021
- Revision received February 25, 2022
- Accepted March 9, 2022
- Published online April 6, 2022.
Copyright & Usage
Copyright © 2022 Queme et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
Author Information
- Luis F. Queme1,2,5,
- Adam J. Dourson1,
- Megan C. Hofmann1,
- Ally Butterfield1,
- Rudolph D. Paladini3 and
- Michael P. Jankowski1,2,4,5
- 1Department of Anesthesia, Division of Pain Management, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
- 2Department of Anesthesiology, University of Cincinnati, Cincinnati, OH 45229
- 3Halozyme, Inc, San Diego, CA 92121
- 4Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229
- 5Pediatric Pain Research Center, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
- Correspondence should be addressed to Michael P. Jankowski at michael.jankowski{at}cchmc.org.
Author contributions
Author contributions: L.F.Q., R.D.P., and M.P.J. designed research; L.F.Q., A.J.D., M.C.H., and A.B. performed research; L.F.Q. and M.P.J. analyzed data; L.F.Q., A.J.D., and M.P.J. wrote the paper.
Disclosures
This research was performed while under a research contract with Halozyme Inc., manufacturers of the hyaluronidase product used (PEGPH20).
This work was partially supported by a research contract with Halozyme Inc. This work was also supported by the National Institutes of Health Grant R01NS113965 (to M.P.J.).
Funding
Halozyme, Inc
National Institutes of Health
R01NS113965
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