### Figure 6-3

AHP characteristics determined the firing properties of bursts, namely the burst size and intraburst AP frequency. *A*, Larger AHP amplitudes were associated with longer bursts. *A1*, Left, Correlations between AHP amplitude and burst size are found in a cell per cell analysis. Right, Distributions of slopes and correlation coefficients (slope, –2.98 ± 1.92 AP/mV; ES = –0.43; *R*, –0.13 ± 0.12; *t* test *t* = –2.26; *p* = 0.03; *N* = 49). Darker dots correspond to individual fits with *p* < 0.05 (Pearson correlation, corrected for multiple comparisons). *A2*, Linear correlation between average AHP amplitude and average burst size (*R*, correlation coefficient; *p*, Wald test *p*-value; *N* = 49). Each dot represents the average values for a given cell. *B*, Larger AHP amplitudes were associated with higher intraburst frequency. *B1*, Left, Correlations between AHP amplitude and intraburst frequency is found in a cell per cell analysis. Right, Distributions of slopes and correlation coefficients (slope, –3.31 ± 1.36 Hz/mV; ES = –0.69; *R*, –0.33 ± 0.12; *t* test, *t* = –5.23; *p* < 0.0001; *N* = 49). Darker dots correspond to individual fits with *p* < 0.05 (Pearson correlation, corrected for multiple comparisons). *B2*, Linear correlation between average AHP amplitude and average intraburst frequency (*R*, correlation coefficient; *p*, Wald test; *N* = 49). Each dot represents the average values for a given cell. *C*, Faster AHP repolarizations (i.e., larger AHP slopes) were associated with longer bursts. *C1*, Left, Correlations between AHP slope and burst size are found in a cell per cell analysis. Right, Distributions of slopes and correlation coefficients [slope, 38.3 ± 22.7 AP/(mV/ms); ES = 0.48; *p* = 0.002; *R* = 0.24 ± 0.08; *t* test, *t* = 5.79; *p* < 0.0001; *N* = 49). Darker dots correspond to individual fits with *p* < 0.05 (Pearson correlation, corrected for multiple comparisons). *C2*, Linear correlation between average AHP slope average and burst size (*R*, correlation coefficient; *p*, Wald test *p*-value; *N* = 49). *D*, Faster AHP repolarizations (i.e., larger AHP slopes) were associated with higher intraburst frequency. *D1*, Left, Correlations between AHP slope and intraburst frequency are found in a cell per cell analysis. Right, Distributions of slopes and correlation coefficients [slope, 71.0 ± 9.0 Hz/(mV/ms); ES = 2.24; *R*, 0.76 ± 0.07; *t* test, *t* = 21.7; *p* < 0.0001; *N* = 49). Darker dots correspond to individual fits with *p* < 0.05 (Pearson correlation, corrected for multiple comparisons). *D2*, Linear correlation between average AHP slope and average intraburst frequency (*R*, correlation coefficient; *p*, Wald test *p*-value; *N* = 49). Note that correlation coefficients were higher when the AHP slope was considered with respect to the AHP amplitude. Download Figure 6-3, TIF file.