The Conditioning Lesion Response in Dorsal Root Ganglion Neurons Is Inhibited in Oncomodulin Knock-Out Mice

Jon P. Niemi; Talia DeFrancesco-Oranburg; Andrew Cox; Jane A. Lindborg; Franklin D. Echevarria; Jemima McCluskey; Dwayne D. Simmons; Richard E. Zigmond

doi:10.1523/ENEURO.0477-21.2022

Article Information

DOI

https://doi.org/10.1523/ENEURO.0477-21.2022

PubMed

35131866

Published By

Society for Neuroscience

History

Received November 11, 2021
Revision received January 20, 2022
Accepted January 30, 2022
Published online February 7, 2022.

Copyright © 2022 Niemi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

Jon P. Niemi¹,^*,
Talia DeFrancesco-Oranburg¹,^*,
Andrew Cox²,
Jane A. Lindborg¹,
Franklin D. Echevarria¹,
Jemima McCluskey²,
Dwayne D. Simmons² and
Richard E. Zigmond¹

¹Case Western Reserve University, Cleveland, OH 44106-4975
²Department of Biology, Baylor University, Waco, TX 76798

Correspondence should be addressed to Richard E. Zigmond at rez{at}case.edu.

T. DeFrancesco-Oranburg’s present addresses: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261.
J. A. Lindborg’s present addresses: Lovelace Biomedical Research Institute, Albuquerque, NM 87108.
F. D. Echevarria’s present addresses: Department of Neurology, University of Florida, Gainesville, FL 32608.

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Author contributions

Author contributions: J.P.N., T.D.-O., J.A.L., F.D.E., D.D.S., and R.E.Z. designed research; J.P.N., T.D.-O., A.C., J.A.L., F.D.E., and J.M. performed research; J.P.N., T.D.-O., J.A.L., F.D.E., and R.E.Z. analyzed data; J.P.N., T.D.-O., and R.E.Z. wrote the paper.
↵* J.P.N. and T.D.-O. contributed equally to this work.

T. DeFrancesco-Oranburg’s present addresses: Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261.
J. A. Lindborg’s present addresses: Lovelace Biomedical Research Institute, Albuquerque, NM 87108.
F. D. Echevarria’s present addresses: Department of Neurology, University of Florida, Gainesville, FL 32608.

Disclosures

The authors declare no competing financial interests.
This work was supported by National Institutes of Health (NIH) Grants NS095017 and DK097223 (to R.E.Z.) and DC00408 and DC013304 (to D.D.S.) and by a 2015-2016 Fulbright Scholar Award (D.D.S.). J.P.N. was supported by training grants NS067431 and NS077888 and J.A.L by training grant NS067431 and an NRSA award (F31NS093694). Use of the Leica SP-8 Confocal Microscope in the Light Microscopy Imaging Facility at Case Western Reserve University (CWRU) made available through the Office of Research Infrastructure (NIH-ORIP) Shared Instrumentation Grant S10OD016164. Breeding and genotyping of animals were carried out by the CWRU Visual Sciences Specialized Animal Resources and the Molecular Biology and Genotyping Cores (EY11373).