Article Information
- Received October 27, 2021
- Revision received December 22, 2021
- Accepted January 3, 2022
- Published online January 19, 2022.
Author Information
- Epifanio Bagarinao1,2,
- Hirohisa Watanabe2,3,4,
- Satoshi Maesawa2,5,
- Kazuya Kawabata2,4,
- Kazuhiro Hara4,
- Reiko Ohdake3,
- Aya Ogura4,
- Daisuke Mori2,
- Noritaka Yoneyama4,
- Kazunori Imai4,
- Takamasa Yokoi4,
- Toshiyasu Kato4,
- Shuji Koyama1,2,
- Masahisa Katsuno4,
- Toshihiko Wakabayashi5,
- Masafumi Kuzuya6,
- Minoru Hoshiyama1,2,
- Haruo Isoda1,2,
- Shinji Naganawa7,
- Norio Ozaki2,8 and
- Gen Sobue2,9
- 1Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Aichi 461-8673, Japan
- 2Brain & Mind Research Center, Nagoya University, Nagoya, Aichi 466-8550, Japan
- 3Department of Neurology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
- 4Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan
- 5Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan
- 6Department of Community Healthcare and Geriatrics, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan
- 7Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan
- 8Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan
- 9Aichi Medical University, Nagakute, Aichi 480-1195, Japan
- Correspondence should be addressed to Hirohisa Watanabe at nabe{at}med.nagoya-u.ac.jp or Epifanio Bagarinao at ebagarinao{at}met.nagoya-u.ac.jp.
Author contributions
Author contributions: H.W., M.Ka., T.W., M.Ku., M.H., H.I., S.N., N.O., and G.S. designed research; S.M., K.K., K.H., R.O., A.O., D.M., N.Y., K.I., T.Y., T.K., S.K., M.H., and H.I. performed research; E.B., H.W., S.M., K.K., and K.H. analyzed data; E.B. and H.W. wrote the paper.
Disclosures
The authors declare no competing financial interests.
This work was supported by Grants-in-Aid from the Research Committee of Central Nervous System Degenerative Diseases by the Ministry of Health, Labour, and Welfare and from the Integrated Research on Neuropsychiatric Disorders project carried out under the Strategic Research for Brain Sciences by the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) of Japan. This work was also supported by the Grant-in-Aid for Scientific Research 80569781 and the Grant-in-Aid for Scientific Research on Innovative Areas (Brain Protein Aging and Dementia Control) 26117002 from MEXT, Japan.
Funding
Ministry of Health, Labour and Welfare (MHLW)
Ministry of Education, Culture, Sports, Science, and Technology (MEXT)
80569781; 26117002
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