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Research ArticleResearch Article: New Research, Development

Distinct Opsin 3 (Opn3) Expression in the Developing Nervous System during Mammalian Embryogenesis

Wayne I. L. Davies, Soufien Sghari, Brian A. Upton, Christoffer Nord, Max Hahn, Ulf Ahlgren, Richard A. Lang and Lena Gunhaga
eNeuro 20 August 2021, 8 (5) ENEURO.0141-21.2021; https://doi.org/10.1523/ENEURO.0141-21.2021
Wayne I. L. Davies
1Umeå Centre for Molecular Medicine (UCMM), Umeå University, Umeå 901 87, Sweden
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Soufien Sghari
1Umeå Centre for Molecular Medicine (UCMM), Umeå University, Umeå 901 87, Sweden
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Brian A. Upton
2Medical Scientist Training Program, University of Cincinnati, Cincinnati, OH 45229
3The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
4Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
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Christoffer Nord
1Umeå Centre for Molecular Medicine (UCMM), Umeå University, Umeå 901 87, Sweden
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Max Hahn
1Umeå Centre for Molecular Medicine (UCMM), Umeå University, Umeå 901 87, Sweden
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Ulf Ahlgren
1Umeå Centre for Molecular Medicine (UCMM), Umeå University, Umeå 901 87, Sweden
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Richard A. Lang
3The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
4Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
5Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
6Department of Ophthalmology, University of Cincinnati, College of Medicine, Cincinnati, OH 45221
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Lena Gunhaga
1Umeå Centre for Molecular Medicine (UCMM), Umeå University, Umeå 901 87, Sweden
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0141-21.2021
PubMed 
34417283
Published By 
Society for Neuroscience
History 
  • Received March 31, 2021
  • Revision received August 6, 2021
  • Accepted August 11, 2021
  • Published online August 20, 2021.
Copyright & Usage 
Copyright © 2021 Davies et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Wayne I. L. Davies1,*,
  2. Soufien Sghari1,*,
  3. Brian A. Upton2,3,4,*,
  4. Christoffer Nord1,
  5. Max Hahn1,
  6. Ulf Ahlgren1,
  7. Richard A. Lang3,4,5,6 and
  8. Lena Gunhaga1
  1. 1Umeå Centre for Molecular Medicine (UCMM), Umeå University, Umeå 901 87, Sweden
  2. 2Medical Scientist Training Program, University of Cincinnati, Cincinnati, OH 45229
  3. 3The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
  4. 4Center for Chronobiology, Division of Pediatric Ophthalmology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
  5. 5Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229
  6. 6Department of Ophthalmology, University of Cincinnati, College of Medicine, Cincinnati, OH 45221
  1. Correspondence should be addressed to Lena Gunhaga at lena.gunhaga{at}umu.se.
View Full Text

Author contributions

  1. Author contributions: R.A.L. and L.G. designed research; W.I.L.D., S.S., B.A.U., C.N., and M.H. performed research; W.I.L.D., S.S., B.A.U., C.N., M.H., U.A., R.A.L., and L.G. analyzed data; W.I.L.D., S.S., and L.G. wrote the paper.

  2. ↵* W.I.L.D., S.S., and B.A.U. contributed equally to this work.

Disclosures

  • The authors declare no competing financial interests.

  • This research conducted in the Gunhaga laboratory was supported by the Swedish Research Council Grant 2017-01430, Insamlingsstiftelsen, Medical Faculty at Umeå University, and the Kempestiftelserna Grant SMK-1763. Work in the Lang laboratory was supported by National Institutes of Health Grants R01EY027077, R01EY027711, R01EY032029, and T32GM063483. Work in the Ahlgren laboratory was supported by the Swedish Research Council Grant 2017-01307 and Insamlingsstiftelsen, Medical Faculty at Umeå.

Funding

  • Swedish Research Council

    2017-01430; 2017-01307
  • Insamlingsstiftelsen, Medical Faculty, Umeå University

  • Kempestiftelserna (Kempe Foundations)

    SMK-1763
  • HHS | National Institutes of Health (NIH)

    R01EY027077; R01EY027711; R01EY032029 and T32GM063483

Other Version

  • You are viewing the most recent version of this article.
  • previous version (August 20, 2021).

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Article usage: August 2021 to June 2025

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Aug 20211770112
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Jul 2024712739
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Jan 20251214333
Feb 20251217822
Mar 2025816738
Apr 2025512724
May 20251213915
Jun 20251411227
Total 202563866159
Total85187641645
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Distinct Opsin 3 (Opn3) Expression in the Developing Nervous System during Mammalian Embryogenesis
Wayne I. L. Davies, Soufien Sghari, Brian A. Upton, Christoffer Nord, Max Hahn, Ulf Ahlgren, Richard A. Lang, Lena Gunhaga
eNeuro 20 August 2021, 8 (5) ENEURO.0141-21.2021; DOI: 10.1523/ENEURO.0141-21.2021

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Distinct Opsin 3 (Opn3) Expression in the Developing Nervous System during Mammalian Embryogenesis
Wayne I. L. Davies, Soufien Sghari, Brian A. Upton, Christoffer Nord, Max Hahn, Ulf Ahlgren, Richard A. Lang, Lena Gunhaga
eNeuro 20 August 2021, 8 (5) ENEURO.0141-21.2021; DOI: 10.1523/ENEURO.0141-21.2021
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Keywords

  • brain
  • development
  • encephalopsin
  • nervous system
  • Opn3
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