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Research ArticleResearch Article: New Research, Disorders of the Nervous System

Modeling Neurodevelopmental Disorders and Epilepsy Caused by Loss of Function of kif2a in Zebrafish

Michèle Partoens, Ann-Sofie De Meulemeester, Hoi-Khoanh Giong, Duc-Hung Pham, Jeong-Soo Lee, Peter A. de Witte and Aleksandra Siekierska
eNeuro 17 August 2021, 8 (5) ENEURO.0055-21.2021; DOI: https://doi.org/10.1523/ENEURO.0055-21.2021
Michèle Partoens
1Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium
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Ann-Sofie De Meulemeester
1Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium
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  • ORCID record for Ann-Sofie De Meulemeester
Hoi-Khoanh Giong
2Disease Target Structure Research Centre, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea
3KRIBB School, University of Science and Technology, Daejeon 34141, Republic of Korea
4Dementia DTC R&D Convergence Program, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea
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Duc-Hung Pham
1Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium
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Jeong-Soo Lee
2Disease Target Structure Research Centre, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea
3KRIBB School, University of Science and Technology, Daejeon 34141, Republic of Korea
4Dementia DTC R&D Convergence Program, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea
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Peter A. de Witte
1Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium
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Aleksandra Siekierska
1Laboratory for Molecular Biodiscovery, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium
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  • ORCID record for Aleksandra Siekierska
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eneuro: 8 (5)
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September/October 2021
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Modeling Neurodevelopmental Disorders and Epilepsy Caused by Loss of Function of kif2a in Zebrafish
Michèle Partoens, Ann-Sofie De Meulemeester, Hoi-Khoanh Giong, Duc-Hung Pham, Jeong-Soo Lee, Peter A. de Witte, Aleksandra Siekierska
eNeuro 17 August 2021, 8 (5) ENEURO.0055-21.2021; DOI: 10.1523/ENEURO.0055-21.2021

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Modeling Neurodevelopmental Disorders and Epilepsy Caused by Loss of Function of kif2a in Zebrafish
Michèle Partoens, Ann-Sofie De Meulemeester, Hoi-Khoanh Giong, Duc-Hung Pham, Jeong-Soo Lee, Peter A. de Witte, Aleksandra Siekierska
eNeuro 17 August 2021, 8 (5) ENEURO.0055-21.2021; DOI: 10.1523/ENEURO.0055-21.2021
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Keywords

  • drug-resistant epilepsy
  • KIF2A
  • malformations of cortical development
  • seizures
  • zebrafish

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