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Research ArticleResearch Article: New Research, Development

Sex and Pubertal Differences in the Maturational Trajectories of Sleep Spindles in the Transition from Childhood to Adolescence: A Population-Based Study

Anna Ricci, Fan He, Susan L. Calhoun, Jidong Fang, Alexandros N. Vgontzas, Duanping Liao, Edward O. Bixler, Magdy Younes and Julio Fernandez-Mendoza
eNeuro 24 June 2021, 8 (4) ENEURO.0257-21.2021; https://doi.org/10.1523/ENEURO.0257-21.2021
Anna Ricci
1Sleep Research and Treatment Center, Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA17033
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Fan He
2Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA17033
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Susan L. Calhoun
1Sleep Research and Treatment Center, Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA17033
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Jidong Fang
1Sleep Research and Treatment Center, Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA17033
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Alexandros N. Vgontzas
1Sleep Research and Treatment Center, Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA17033
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Duanping Liao
2Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA17033
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Edward O. Bixler
1Sleep Research and Treatment Center, Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA17033
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Magdy Younes
3Sleep Disorders Centre, University of Manitoba, Winnipeg, ManitobaR3M 0A7, Canada
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Julio Fernandez-Mendoza
1Sleep Research and Treatment Center, Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA17033
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Article Information

DOI 
https://doi.org/10.1523/ENEURO.0257-21.2021
PubMed 
34168053
Published By 
Society for Neuroscience
History 
  • Received June 7, 2021
  • Accepted June 10, 2021
  • Published online June 24, 2021.
Copyright & Usage 
Copyright © 2021 Ricci et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

Author Information

  1. Anna Ricci1,
  2. Fan He2,
  3. Susan L. Calhoun1,
  4. Jidong Fang1,
  5. Alexandros N. Vgontzas1,
  6. Duanping Liao2,
  7. Edward O. Bixler1,
  8. Magdy Younes3 and
  9. Julio Fernandez-Mendoza1
  1. 1Sleep Research and Treatment Center, Department of Psychiatry and Behavioral Health, Penn State College of Medicine, Hershey, PA17033
  2. 2Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA17033
  3. 3Sleep Disorders Centre, University of Manitoba, Winnipeg, ManitobaR3M 0A7, Canada
  1. Correspondence should be addressed to Julio Fernandez-Mendoza at jfmendoza{at}psu.edu.
View Full Text

Author contributions

  1. Author contributions: A.R. and J.F.-M. designed research; A.R., F.H., J.F., M.Y., and J.F.-M. performed research; F.H. and D.L. analyzed data; A.R., F.H., S.L.C., J.F., A.N.V., D.L., E.O.B., M.Y., and J.F.-M. wrote the paper.

Disclosures

  • J.F. discloses ownership of Biosoft Studio (Hershey, PA), which developed and maintains sleep FFT software. M.Y. discloses having developed, and having a patent on, the spindle analysis technology, which has been licensed to Cerebra Health (Winnipeg, Manitoba, Canada), and he is a shareholder and receives royalties and consultation fees from Cerebra Health. All other authors declare no competing financial interests.

  • This work was supported by the National Institute of Mental Health; National Heart, Lung, and Blood Institute; and the National Center for Advancing Translational Sciences of the National Institutes of Health under Grants R01MH118308, R01HL136587, R01HL97165, R01HL63772, and UL1TR000127.

Funding

  • HHS | NIH | National Institute of Mental Health (NIMH)

    R01MH118308
  • HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI)

    R01HL136587; R01HL97165; R01HL63772

Other Version

  • You are viewing the most recent version of this article.
  • previous version (June 24, 2021).

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Article usage: June 2021 to March 2026

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Jun 2021137038
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Oct 20211515853
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Total 20217421146358
Jan 2022108227
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Apr 202235326
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Jul 202307415
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Total 202360886179
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Total 20251291313260
Jan 20262115562
Feb 2026920526
Mar 20261163
Total 20263137691
Total109354651332
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Sex and Pubertal Differences in the Maturational Trajectories of Sleep Spindles in the Transition from Childhood to Adolescence: A Population-Based Study
Anna Ricci, Fan He, Susan L. Calhoun, Jidong Fang, Alexandros N. Vgontzas, Duanping Liao, Edward O. Bixler, Magdy Younes, Julio Fernandez-Mendoza
eNeuro 24 June 2021, 8 (4) ENEURO.0257-21.2021; DOI: 10.1523/ENEURO.0257-21.2021

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Sex and Pubertal Differences in the Maturational Trajectories of Sleep Spindles in the Transition from Childhood to Adolescence: A Population-Based Study
Anna Ricci, Fan He, Susan L. Calhoun, Jidong Fang, Alexandros N. Vgontzas, Duanping Liao, Edward O. Bixler, Magdy Younes, Julio Fernandez-Mendoza
eNeuro 24 June 2021, 8 (4) ENEURO.0257-21.2021; DOI: 10.1523/ENEURO.0257-21.2021
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Keywords

  • adolescence
  • brain maturation
  • childhood
  • developmental biology
  • puberty
  • sleep spindles

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